Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Dithiazanine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 7/20 | 1.00 |
| ▸ | NPC1 | O15118 | 5/20 | 1.00 |
| ▸ | RAB9A | P51151 | 5/20 | 1.00 |
| ▸ | HTT | P42858 | 5/20 | 1.00 |
| ▸ | BLM | P54132 | 4/20 | 1.00 |
| ▸ | MAPT | P10636 | 4/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 1.00 |
| ▸ | THRB | P10828 | 3/20 | 1.00 |
| ▸ | POLB | P06746 | 2/20 | 1.00 |
| ▸ | PKM | P14618 | 2/20 | 1.00 |
| ▸ | RECQL | P46063 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | USP2 | O75604 | 2/20 | 1.00 |
| ▸ | ALOX12 | P18054 | 2/20 | 1.00 |
| ▸ | CTNNB1 | P35222 | 2/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL7761426 | 1.00 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| Iodide SCHEMBL139369 | 1.00 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| Iodide SCHEMBL29393130 | 1.00 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| Dithiazanine SCHEMBL22877 | 1.00 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| Dithiazanine SCHEMBL77427 | 1.00 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| Iodide SCHEMBL335663 | 1.00 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| Dithiazanine SCHEMBL142280 | 1.00 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| Dithiazanine SCHEMBL29459605 | 1.00 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| SCHEMBL13898198 | 0.99 | KMT2A (1.00) | MEN1KMT2ANPC1RAB9AHTT | |
| Dithiazanine SCHEMBL1567134 | 0.99 | KMT2A (1.00) | MEN1KMT2ANPC1RAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 352 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025042167-A1 | PHOTOINITIATIED COPOLYMER RESIN, SEPARATOR CONTAINING CROSS-LINKED STRUCTURE FOR LITHIUM SECONDARY BATTERY, AND METHOD FOR MANUFACTURING SAME | 주식회사 엘지화학 | 2025-02-27 | — | — | WO | claimed |
| US-12173355-B2 | Nano-plasmonic molecular probes and methods of use | DUKE UNIVERSITY (US) | 2024-12-24 | — | — | US | claimed |
| US-20240402164-A1 | PLASMONIC CAGED NANOPLATFORMS AND METHODS THEREOF | DUKE UNIVERSITY | 2024-12-05 | — | — | US | claimed |
| US-20240401113-A1 | AMPLIFICATION SYSTEMS FOR NANO-PLASMONIC MOLECULAR PROBES AND METHODS THEREOF | DUKE UNIVERSITY | 2024-12-05 | — | — | US | claimed |
| US-12129437-B2 | Method for the dissolution of amorphous dithiazines | CONOCOPHILLIPS COMPANY (US) | 2024-10-29 | — | — | US | claimed |
| EP-4445150-A1 | SULFUR AND AMORPHOUS DITHIAZINE MEASUREMENT | CONOCOPHILLIPS COMPANY (US) | 2024-10-16 | — | — | EP | claimed |
| US-12006493-B2 | Nitrile solvents | ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) | 2024-06-11 | — | — | US | claimed |
| US-20240156993-A1 | PLASMONICS SENSING NANOPLATFORMS FOR HUMAN STEM CELL APPLICATIONS AND METHODS THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2024-05-16 | — | — | US | claimed |
| EP-4225511-A1 | METHOD FOR THE DISSOLUTION OF AMORPHOUS DITHIAZINES | Conocophillips Company (US) | 2023-08-16 | — | — | EP | claimed |
| EP-4217585-A1 | NITRILE SOLVENTS | Ascend Performance Materials Operations LLC (US) | 2023-08-02 | — | — | EP | claimed |
| US-20220233628-A1 | PLASMONICS-ACTIVE METAL NANOSTAR COMPOSITIONS AND METHODS OF USE | DUKE UNIVERSITY | 2022-07-28 | — | — | US | claimed |
| US-11374179-B2 | Dithiazine-based hole transport material, preparing method thereof, and organic light-emitting device | WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) | 2022-06-28 | — | — | US | claimed |
| US-20220149297-A1 | DITHIAZINE-BASED HOLE TRANSPORT MATERIAL, PREPARING METHOD THEREOF, AND ORGANIC LIGHT-EMITTING DEVICE | WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) | 2022-05-12 | — | — | US | claimed |
| US-11324797-B2 | Plasmonics-active metal nanostar compositions and methods of use | DUKE UNIVERSITY (US) | 2022-05-10 | — | — | US | claimed |
| EP-3983382-A1 | NOVEL NON-CODING HETEROCYCLIC AMINO ACIDS (NCHAA) AND THEIR USE AS HERBICIDES | Fortephest Ltd. (IL) | 2022-04-20 | — | — | EP | claimed |
| US-20220112443-A1 | METHOD FOR THE DISSOLUTION OF AMORPHOUS DITHIAZINES | CONOCOPHILLIPS COMPANY | 2022-04-14 | — | — | US | claimed |
| WO-2022076460-A1 | METHOD FOR THE DISSOLUTION OF AMORPHOUS DITHIAZINES | CONOCOPHILLIPS COMPANY (US) | 2022-04-14 | — | — | WO | claimed |
| US-20220098526-A1 | NITRILE SOLVENTS | ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) | 2022-03-31 | — | — | US | claimed |
| WO-2022066969-A1 | NITRILE SOLVENTS | ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) | 2022-03-31 | — | — | WO | claimed |
| EP-3569753-B1 | METHODS FOR PRODUCING SPUNBOND NONWOVEN FABRICS MADE FROM CONTINUOUS FIBRES | REIFENHAEUSER MASCH (DE) | 2022-02-16 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220149297-A1 | DITHIAZINE-BASED HOLE TRANSPORT MATERIAL, PREPARING METHOD THEREOF, AND ORGANIC LIGHT-EMITTING DEVICE | FTH1, SLC40A1, TST | MEN1 3460/4885KMT2A 3066/4885NPC1 831/4885 |
| US-11374179-B2 | Dithiazine-based hole transport material, preparing method thereof, and organic light-emitting device | FTH1, SLC40A1, TST | MEN1 3460/4885KMT2A 3066/4885NPC1 831/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.