Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | RGS12 | O14924 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | THPO | P40225 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL27932850 | 0.98 | AKR1B1 (0.56) | AKR1B1CYP1A2CYP2C19LMNAGAA | |
| SCHEMBL70565 | 0.84 | AKR1B1 (0.71) | AKR1B1CYP1A2CYP2C19LMNAGAA | |
| Hydrochloric Acid SCHEMBL8922940 | 0.82 | AKR1B1 (0.68) | AKR1B1CYP1A2CYP2C19LMNAGAA | |
| SCHEMBL13647128 | 0.82 | ALDH1A1 (0.39) | AKR1B1CYP1A2CYP2C19POLBALDH1A1 | |
| SCHEMBL13285692 | 0.82 | CTBP2 (0.39) | AKR1B1MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL10283887 | 0.80 | KEAP1 (0.61) | — | |
| SCHEMBL9113 | 0.79 | AKR1B1 (0.58) | AKR1B1CYP1A2CYP2C19LMNAGAA | |
| SCHEMBL4402323 | 0.78 | AKR1B1 (0.62) | AKR1B1CYP1A2CYP2C19LMNAGAA | |
| Hydrochloric Acid SCHEMBL2531929 | 0.78 | AKR1B1 (0.56) | AKR1B1CYP1A2CYP2C19 | |
| SCHEMBL10291819 | 0.77 | SLC7A5 (0.55) | LMNAGAATSHRKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111566517-B | Contact lens having a lubricious coating thereon | 爱尔康公司 | 2023-11-10 | — | — | CN | claimed |
| CN-117270235-A | Contact lens having a lubricious coating thereon | 爱尔康公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-111566517-B | Contact lens having a lubricious coating thereon | 爱尔康公司 | 2023-11-10 | — | — | CN | disclosed |
| EP-2651862-B1 | SUBSTITUTED TETRAARYLBENZENES | MERCK PATENT GMBH (DE) | 2017-05-10 | — | — | EP | disclosed |
| WO-2008039882-A1 | A COMBINATION OF NIACIN AND A PROSTAGLANDIN D2 RECEPTOR ANTAGONIST | SANOFI-AVENTIS U.S. LLC (US) | 2008-04-03 | — | — | WO | disclosed |
| WO-2007146838-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2007-12-21 | — | — | WO | disclosed |