SCHEMBL8445315

SCHEMBL8445315

O=C1CCCCCCCCCCCC/C=C\O1

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.36
CA9 Q16790 1/20 0.36
ALDH1A1 P00352 2/20 0.34
TRIM24 O15164 1/20 0.32
TRIM33 Q9UPN9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2450670 0.91
SCHEMBL28850383 0.89 ALDH1A1 (0.33) ALDH1A1
SCHEMBL142284 0.80
SCHEMBL701871 0.73
SCHEMBL29962604 0.73 TSHR (0.43) CA1CA9ALDH1A1TRIM24TRIM33
SCHEMBL29962055 0.73 TSHR (0.43) CA1CA9ALDH1A1TRIM24TRIM33
SCHEMBL29962516 0.73 TSHR (0.43) CA1CA9ALDH1A1TRIM24TRIM33
SCHEMBL29962253 0.73 TSHR (0.43) CA1CA9ALDH1A1TRIM24TRIM33
Methoxymethane SCHEMBL8952224 0.73
SCHEMBL29962242 0.73 TSHR (0.43) CA1CA9ALDH1A1TRIM24TRIM33

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0889945-A1 FRAGRANT MACROCYCLIC LACTONES FIRMENICH SA (CH) 1999-01-13 EP disclosed
WO-1997032948-A1 FRAGRANT MACROCYCLIC LACTONES FIRMENICH S.A. (CH) 1997-09-12 WO disclosed