Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12778251 | 0.88 | MEN1 (0.47) | SMN1; SMN2RAB9AKMT2AMEN1MAPT | |
| SCHEMBL12779413 | 0.86 | MEN1 (0.47) | SMN1; SMN2RAB9AKMT2AMEN1MAPT | |
| SCHEMBL12778249 | 0.79 | MEN1 (0.47) | SMN1; SMN2RAB9AKMT2AMEN1MAPT | |
| SCHEMBL12777765 | 0.76 | PKM (0.43) | SMN1; SMN2RAB9AKMT2AMAPTMAPK1 | |
| SCHEMBL14199904 | 0.75 | MEN1 (0.52) | SMN1; SMN2RAB9AKMT2AMEN1MAPT | |
| SCHEMBL15679923 | 0.73 | MAPT (0.41) | SMN1; SMN2RAB9AKMT2AMEN1MAPT | |
| SCHEMBL12779412 | 0.73 | SENP5 (0.49) | SMN1; SMN2RAB9AKMT2AMEN1MAPT | |
| SCHEMBL12777764 | 0.73 | TSHR (0.49) | SMN1; SMN2KMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL14450788 | 0.71 | GRIN2D (0.40) | RAB9AMAPTALDH1A1LMNAPOLB | |
| SCHEMBL14228256 | 0.70 | GRIN2D (0.45) | RAB9AKMT2AMAPTMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778874-B2 | Glycopeptide antibiotic monomer derivatives | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-07-15 | — | — | US | disclosed |
| US-20080097078-A1 | Antibacterial activity against vancomycin-resistant bacteria | SHIONOGI & CO., LTD. (JP) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080097078-A1 | Antibacterial activity against vancomycin-resistant bacteria | CSGALNACT1, MON2, NR2C2 | SMN1; SMN2 3927/4885RAB9A 2738/4885KMT2A 2424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.