Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 4/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | VDR | P11473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13475542 | 0.82 | TSHR (0.47) | ACHEALOX15HTTSMN1; SMN2CYP1A2 | |
| SCHEMBL14183053 | 0.80 | PKM (0.45) | PKMSLC22A12HTTSMN1; SMN2KDM4E | |
| SCHEMBL13475564 | 0.79 | VDR (0.39) | ACHETHRATHRBSCN4AALOX15 | |
| SCHEMBL14200182 | 0.77 | VDR (0.43) | ACHESMN1; SMN2VDRKDM4ECYP1A2 | |
| SCHEMBL28385292 | 0.75 | PKM (0.47) | PKMSLC22A12SMN1; SMN2CYP1A2 | |
| SCHEMBL12044516 | 0.75 | TSHR (0.44) | PKMSLC22A12SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL10271333 | 0.75 | PKM (0.42) | PKMSLC22A12ALOX15HTTSMN1; SMN2 | |
| SCHEMBL10285685 | 0.74 | KDM4E (0.58) | SCN4AALOX15HTTSMN1; SMN2KDM4E | |
| SCHEMBL8303063 | 0.74 | PKM (0.44) | PKMSLC22A12KEAP1NFE2L2SMN1; SMN2 | |
| SCHEMBL20708116 | 0.74 | PKM (0.41) | ACHEPKMBCHEHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080097078-A1 | Antibacterial activity against vancomycin-resistant bacteria | SHIONOGI & CO., LTD. (JP) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080097078-A1 | Antibacterial activity against vancomycin-resistant bacteria | CSGALNACT1, MON2, NR2C2 | ACHE 4329/4885PKM 3014/4885SLC22A12 362/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.