Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14229081 | 0.92 | RIPK1 (0.39) | RIPK1 | |
| SCHEMBL14229303 | 0.90 | RIPK1 (0.43) | RIPK1 | |
| SCHEMBL14229011 | 0.90 | RIPK1 (0.43) | RIPK1 | |
| SCHEMBL14201161 | 0.88 | RIPK1 (0.32) | RIPK1S1PR1 | |
| SCHEMBL14229311 | 0.88 | RIPK1 (0.47) | RIPK1 | |
| SCHEMBL14200779 | 0.85 | PSEN1 (0.32) | RIPK1 | |
| SCHEMBL14229009 | 0.85 | RIPK1 (0.41) | RIPK1 | |
| SCHEMBL14230199 | 0.85 | RIPK1 (0.45) | RIPK1 | |
| SCHEMBL14201160 | 0.83 | S1PR1 (0.33) | S1PR1 | |
| SCHEMBL14229510 | 0.81 | MEN1 (0.34) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |