Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 3/20 | 0.43 |
| ▸ | GLI1 | P08151 | 2/20 | 0.35 |
| ▸ | GLI2 | P10070 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14229307 | 0.92 | MLYCD (0.45) | MLYCD | |
| SCHEMBL14201190 | 0.84 | MLYCD (0.44) | MLYCDGLI1GLI2 | |
| SCHEMBL14230196 | 0.82 | CYP1A2 (0.34) | — | |
| SCHEMBL14229087 | 0.80 | GAA (0.34) | — | |
| SCHEMBL14230059 | 0.80 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL14229005 | 0.79 | MLYCD (0.48) | MLYCD | |
| SCHEMBL14229498 | 0.79 | GAA (0.34) | — | |
| SCHEMBL14229428 | 0.79 | TP53 (0.50) | MLYCD | |
| SCHEMBL14230195 | 0.78 | POLB (0.34) | MLYCD | |
| SCHEMBL14201189 | 0.77 | MLYCD (0.46) | MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |