Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 7/20 | 0.44 |
| ▸ | GLI1 | P08151 | 2/20 | 0.36 |
| ▸ | GLI2 | P10070 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14201189 | 0.93 | MLYCD (0.46) | MLYCD | |
| SCHEMBL14229488 | 0.84 | MLYCD (0.43) | MLYCDGLI1GLI2 | |
| SCHEMBL14201180 | 0.81 | S1PR1 (0.34) | MLYCD | |
| SCHEMBL14201179 | 0.81 | S1PR1 (0.33) | MLYCD | |
| SCHEMBL14201162 | 0.80 | MLYCD (0.36) | MLYCDRXRARXRBRXRG | |
| SCHEMBL14201160 | 0.80 | S1PR1 (0.33) | MLYCD | |
| SCHEMBL14201171 | 0.80 | MLYCD (0.49) | MLYCD | |
| SCHEMBL14201194 | 0.80 | S1PR1 (0.32) | — | |
| SCHEMBL14201158 | 0.79 | MLYCD (0.33) | MLYCD | |
| SCHEMBL14200764 | 0.79 | ALDH1A1 (0.38) | MLYCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |