Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.62 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.38 |
| ▸ | CDK1 | P06493 | 2/20 | 0.38 |
| ▸ | CDK4 | P11802 | 2/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.38 |
| ▸ | CCND1 | P24385 | 2/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | CDK7 | P50613 | 1/20 | 0.38 |
| ▸ | CCNH | P51946 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL142294 | 1.00 | HDAC8 (0.62) | HDAC8CCNT1CDK1CDK4CCNB1 | |
| SCHEMBL137428 | 0.86 | HDAC8 (0.43) | HDAC8KEAP1CA12CA1CA2 | |
| SCHEMBL137429 | 0.86 | HDAC8 (0.43) | HDAC8KEAP1CA12CA1CA2 | |
| SCHEMBL139430 | 0.78 | — | — | |
| SCHEMBL139295 | 0.78 | CCNT1 (0.50) | HDAC8CCNT1CDK1CDK4CCNB1 | |
| SCHEMBL106526 | 0.78 | CCNT1 (0.50) | HDAC8CCNT1CDK1CDK4CCNB1 | |
| SCHEMBL9861869 | 0.77 | ALDH1A1 (0.57) | HDAC8TRPA1MAPTMEN1NPC1 | |
| SCHEMBL9861852 | 0.77 | ALDH1A1 (0.57) | HDAC8TRPA1MAPTMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL1190733 | 0.76 | — | — | |
| SCHEMBL14123783 | 0.76 | NPC1 (0.45) | HDAC8CA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2433131-B1 | Particles for long wavelength SERS, method of manufacture and method for tagging a material | SICPA HOLDING SA (CH) | 2016-07-06 | — | — | EP | claimed |
| US-9239327-B2 | Particles comprising hollow surface-enhanced spectroscopy (SES)-active core for long wavelength SERS | SICPA HOLDING SA (CH) | 2016-01-19 | — | — | US | claimed |
| EP-2433131-A1 | PARTICLES AND METHODS FOR LONG WAVELENGTH SERS | Cabot Security Materials Inc. (US) | 2012-03-28 | — | — | EP | claimed |
| US-20120057165-A1 | Particles and Methods for Long Wavelength SERS | CABOT SECURITY MATERIALS INC. (US) | 2012-03-08 | — | — | US | claimed |
| WO-2010135354-A1 | PARTICLES AND METHODS FOR LONG WAVELENGTH SERS | OXONICA MATERIALS INC. (US) | 2010-11-25 | — | — | WO | claimed |
| EP-2433131-B1 | Particles for long wavelength SERS, method of manufacture and method for tagging a material | SICPA HOLDING SA (CH) | 2016-07-06 | — | — | EP | disclosed |
| US-9239327-B2 | Particles comprising hollow surface-enhanced spectroscopy (SES)-active core for long wavelength SERS | SICPA HOLDING SA (CH) | 2016-01-19 | — | — | US | disclosed |
| EP-2433131-A1 | PARTICLES AND METHODS FOR LONG WAVELENGTH SERS | Cabot Security Materials Inc. (US) | 2012-03-28 | — | — | EP | disclosed |
| US-20120057165-A1 | Particles and Methods for Long Wavelength SERS | CABOT SECURITY MATERIALS INC. (US) | 2012-03-08 | — | — | US | disclosed |
| WO-2010135354-A1 | PARTICLES AND METHODS FOR LONG WAVELENGTH SERS | OXONICA MATERIALS INC. (US) | 2010-11-25 | — | — | WO | disclosed |