SCHEMBL106526

SCHEMBL106526

c1cc(/N=N/c2ccncc2)ccn1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCNT1 O60563 2/20 0.50
CDK1 P06493 2/20 0.50
CDK4 P11802 2/20 0.50
CCNB1 P14635 2/20 0.50
CCND1 P24385 2/20 0.50
CCNE1 P24864 2/20 0.50
CDK2 P24941 2/20 0.50
CDK9 P50750 2/20 0.50
PLG P00747 1/20 0.50
CDK7 P50613 1/20 0.50
CCNH P51946 1/20 0.50
MAPT P10636 3/20 0.47
LMNA P02545 2/20 0.47
ALDH1A1 P00352 2/20 0.44
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
HDAC8 Q9BY41 2/20 0.42
CYP2D6 P10635 1/20 0.42
CHRM1 P11229 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL139295 1.00 CCNT1 (0.50) CCNT1CDK1CDK4CCNB1CCND1
SCHEMBL3291148 0.88 ALDH1A1 (0.67) CCNT1CDK1CDK4CCNB1CCND1
SCHEMBL3291145 0.88 ALDH1A1 (0.67) CCNT1CDK1CDK4CCNB1CCND1
SCHEMBL28552816 0.84 GLB1 (0.56) CCNT1CDK1CDK4CCNB1CCND1
SCHEMBL146200 0.84 CCNT1 (0.41) CCNT1CDK1CDK4CCNB1CCND1
SCHEMBL14366689 0.84 MAPT (0.70) CCNT1CDK1CDK4CCNB1CCND1
SCHEMBL146201 0.84 CCNT1 (0.41) CCNT1CDK1CDK4CCNB1CCND1
SCHEMBL4349980 0.84 NPC1 (0.58) CCNT1CDK1CDK4CCNB1CCND1
SCHEMBL4349981 0.84 NPC1 (0.58) CCNT1CDK1CDK4CCNB1CCND1
SCHEMBL17527053 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12636634-B2 Fluorinated MOF materials having rectangular channels, method of synthesizing MOF materials and methods of using MOF materials including for CO2 capture KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2026-05-26 US claimed
US-20240316530-A1 FLUORINATED MOF MATERIALS HAVING RECTANGULAR CHANNELS, METHOD OF SYNTHESIZING MOF MATERIALS AND METHODS OF USING MOF MATERIALS INCLUDING FOR CO2 CAPTURE KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2024-09-26 US claimed
WO-2024196666-A1 FLUORINATED MOF MATERIALS HAVING RECTANGULAR CHANNELS, METHOD OF SYNTHESIZING MOF MATERIALS AND METHODS OF USING MOF MATERIALS INCLUDING FOR CO2 CAPTURE KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2024-09-26 WO claimed
CN-109422771-B Hydrothermally stable anion pillared hybrid porous material and preparation method and application thereof 浙江大学 2020-07-24 CN claimed
CN-109420480-B Method for separating carbon tetraolefin mixture 浙江大学 2020-06-09 CN claimed
CN-108558917-B Zinc-furandicarboxylic acid organic framework material and preparation method thereof 江西省科学院应用化学研究所 2020-03-31 CN claimed
US-9856190-B2 1, 3-butadiene separating material, and separation method using said separating material SHOWA DENKO K.K. (JP) 2018-01-02 US claimed
US-20160159712-A1 1, 3-BUTADIENE SEPARATING MATERIAL, AND SEPARATION METHOD USING SAID SEPARATING MATERIAL SHOWA DENKO K.K. (JP) 2016-06-09 US claimed
US-4180569-A 4,4*-AZODIPYRIDINE AND ITS SALTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-12-25 US claimed
US-12636634-B2 Fluorinated MOF materials having rectangular channels, method of synthesizing MOF materials and methods of using MOF materials including for CO2 capture KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2026-05-26 US disclosed
US-12629639-B2 Spacer for a spiral wound membrane EVOVE LTD (GB) 2026-05-19 US disclosed
US-20240316530-A1 FLUORINATED MOF MATERIALS HAVING RECTANGULAR CHANNELS, METHOD OF SYNTHESIZING MOF MATERIALS AND METHODS OF USING MOF MATERIALS INCLUDING FOR CO2 CAPTURE KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2024-09-26 US disclosed
WO-2024196666-A1 FLUORINATED MOF MATERIALS HAVING RECTANGULAR CHANNELS, METHOD OF SYNTHESIZING MOF MATERIALS AND METHODS OF USING MOF MATERIALS INCLUDING FOR CO2 CAPTURE KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2024-09-26 WO disclosed
EP-4397399-A2 MEMBRANES COMPRISING A LAYER OF METAL ORGANIC FRAMEWORK PARTICLES G2O Water Technologies Limited (GB) 2024-07-10 EP disclosed
US-9239327-B2 Particles comprising hollow surface-enhanced spectroscopy (SES)-active core for long wavelength SERS SICPA HOLDING SA (CH) 2016-01-19 US disclosed
US-20120057165-A1 Particles and Methods for Long Wavelength SERS CABOT SECURITY MATERIALS INC. (US) 2012-03-08 US disclosed
US-20120057165-A1 Particles and Methods for Long Wavelength SERS CABOT SECURITY MATERIALS INC. (US) 2012-03-08 US disclosed
WO-2010133849-A1 DETECTION OF TARGET ANALYTE BY SIGNAL AMPLIFICATION RENISHAW DIAGNOSTICS LIMITED (GB) 2010-11-25 WO disclosed
US-4180569-A 4,4*-AZODIPYRIDINE AND ITS SALTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-12-25 US disclosed
US-4180569-A 4,4*-AZODIPYRIDINE AND ITS SALTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1979-12-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160159712-A1 1, 3-BUTADIENE SEPARATING MATERIAL, AND SEPARATION METHOD USING SAID SEPARATING MATERIAL MSL1, LANCL2, ACSL1 CCNT1 237/4885CDK1 412/4885CDK4 1337/4885
US-12636634-B2 Fluorinated MOF materials having rectangular channels, method of synthesizing MOF materials and methods of using MOF materials including for CO2 capture MLX, BMP4, F13B CCNT1 2962/4885CDK1 2255/4885CDK4 2077/4885
US-12629639-B2 Spacer for a spiral wound membrane AQP1, AQP3, AQP4 CCNT1 782/4885CDK1 2107/4885CDK4 1041/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.