Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | SYK | P43405 | 1/20 | 0.53 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31302305 | 0.91 | MEN1 (0.63) | MEN1MAPTKMT2APOLBLMNA | |
| SCHEMBL11795454 | 0.91 | MEN1 (0.63) | MEN1MAPTKMT2APOLBLMNA | |
| SCHEMBL14236870 | 0.85 | MEN1 (0.74) | MEN1MAPTKMT2AMAPK1NFKB1 | |
| SCHEMBL31149857 | 0.85 | MAPT (0.57) | MEN1MAPTKMT2AMAPK1POLB | |
| SCHEMBL11582751 | 0.85 | MAPT (0.57) | MEN1MAPTKMT2AMAPK1POLB | |
| SCHEMBL30562985 | 0.85 | MEN1 (0.74) | MEN1MAPTKMT2AMAPK1NFKB1 | |
| SCHEMBL13771495 | 0.85 | ALDH1A1 (0.64) | MEN1MAPTKMT2AMAPK1NFKB1 | |
| SCHEMBL13421105 | 0.84 | MAPT (0.55) | MEN1MAPTKMT2AMAPK1POLB | |
| SCHEMBL20820089 | 0.83 | NFKB1 (0.76) | MEN1MAPTKMT2AMAPK1NFKB1 | |
| SCHEMBL14118005 | 0.82 | IDH2 (0.61) | MEN1MAPTKMT2APOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080096220-A1 | NOVEL TRIAZINE-BASED DETOXIFICATION AGENTS AND THEIR USE | ASTREA UK SERVICES LIMITED (GB) | 2008-04-24 | — | — | US | disclosed |