Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 3/20 | 0.55 |
| ▸ | ALPL | P05186 | 2/20 | 0.46 |
| ▸ | ACR | P10323 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14235819 | 0.83 | HCAR3 (0.51) | HCAR3ALPLACRHCAR2ADORA3 | |
| SCHEMBL14213417 | 0.76 | HCAR3 (0.54) | HCAR3ALPLHCAR2SMN1; SMN2ADORA3 | |
| SCHEMBL14235364 | 0.75 | HCAR3 (0.50) | HCAR3ALPLACRHCAR2ADORA3 | |
| SCHEMBL14213422 | 0.75 | HCAR3 (0.57) | HCAR3ALPLACRSMN1; SMN2ADORA3 | |
| SCHEMBL14213418 | 0.73 | HCAR3 (0.50) | HCAR3ALPLACRHCAR2SMN1; SMN2 | |
| SCHEMBL14236018 | 0.72 | ACR (0.60) | HCAR3ALPLACRKMT2AADORA3 | |
| SCHEMBL14235840 | 0.72 | HCAR3 (0.50) | HCAR3KMT2AHCAR2SMN1; SMN2ADORA3 | |
| SCHEMBL14213414 | 0.72 | HCAR3 (0.53) | HCAR3ALPLACRADORA3ADORA2A | |
| SCHEMBL14213426 | 0.72 | HCAR3 (0.53) | HCAR3ALPLACRADORA3ADORA2A | |
| SCHEMBL14235390 | 0.70 | HCAR3 (0.48) | HCAR3ACRHCAR2ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120309773-A1 | HETEROCYCLIC COMPOUNDS AS JANUS KINASE INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. | 2012-12-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309773-A1 | HETEROCYCLIC COMPOUNDS AS JANUS KINASE INHIBITORS | JAK2, JAK1, JAK3 | HCAR3 2267/4885ALPL 4794/4885ACR 4331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.