Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | RGS12 | O14924 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ADCY10 | Q96PN6 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14235853 | 0.81 | MAPT (0.41) | MAPTALDH1A1MEN1KMT2ARECQL | |
| SCHEMBL6689898 | 0.77 | DRD4 (0.41) | DRD4MAPTALDH1A1L3MBTL1ADORA2A | |
| SCHEMBL14235849 | 0.76 | ALDH1A1 (0.42) | DRD4ALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL14214073 | 0.75 | BACE1 (0.39) | DRD4MAPTALDH1A1L3MBTL1S1PR1 | |
| SCHEMBL14236268 | 0.75 | MAPT (0.47) | MAPTALDH1A1L3MBTL1ADORA2AMEN1 | |
| SCHEMBL15428612 | 0.71 | ADORA2A (0.42) | DRD4MAPTALDH1A1ADORA2AMEN1 | |
| SCHEMBL6566313 | 0.71 | HSD11B1 (0.46) | DRD4ALDH1A1HSD17B10ADCY10NPC1 | |
| SCHEMBL23105552 | 0.69 | ALDH1A1 (0.59) | MAPTALDH1A1L3MBTL1S1PR1MEN1 | |
| SCHEMBL22096870 | 0.69 | ALDH1A1 (0.34) | MAPTALDH1A1ADORA2AKDM4EADORA3 | |
| SCHEMBL544412 | 0.68 | KDM4E (0.47) | DRD4MAPTALDH1A1ADORA2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8329703-B2 | Pyrazole compounds | XTL BIOPHARMACEUTICALS LTD. (IL) | 2012-12-11 | — | — | US | disclosed |