Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1625924 | 0.99 | HTR6 (0.36) | HTR6KMT2AP2RX7KDM4EUSP2 | |
| SCHEMBL14237118 | 0.89 | KMT2A (0.35) | HTR6KMT2AP2RX7NPSR1LMNA | |
| SCHEMBL14237013 | 0.88 | L3MBTL1 (0.36) | HTR6KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL4894448 | 0.87 | L3MBTL1 (0.36) | HTR6KMT2AALDH1A1 | |
| SCHEMBL14237057 | 0.86 | SLC6A2 (0.34) | HTR6KMT2AKDM4EUSP2ALDH1A1 | |
| SCHEMBL14237041 | 0.86 | MAPT (0.39) | HTR6KMT2AKDM4EALDH1A1MAPT | |
| SCHEMBL14237048 | 0.86 | HTR6 (0.39) | HTR6KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL14237106 | 0.85 | KMT2A (0.38) | HTR6KMT2AKDM4EUSP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1627696 | 0.85 | MAPT (0.38) | HTR6KMT2AKDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL1625086 | 0.85 | SLC6A2 (0.36) | HTR6KDM4EUSP2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831195-B1 | 5-HT7 RECEPTOR ANTAGONISTS | ESTEVE LABOR DR (ES) | 2012-12-19 | — | — | EP | claimed |