Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.39 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.38 |
| ▸ | HTR2B | P41595 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1628038 | 0.99 | HTR6 (0.38) | HTR6DRD1DRD5HTR2CHTR2B | |
| SCHEMBL14237116 | 0.91 | HTR6 (0.38) | HTR6DRD1DRD5HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL1628011 | 0.90 | HTR6 (0.37) | HTR6HTR2CHTR2BUSP30LMNA | |
| Hydrochloric Acid SCHEMBL1627613 | 0.90 | ALK (0.41) | ALK | |
| SCHEMBL14236970 | 0.89 | DRD1 (0.41) | HTR6DRD1DRD5HTR2CALDH1A1 | |
| Hydrochloric Acid SCHEMBL1627851 | 0.89 | DRD1 (0.40) | HTR6DRD1DRD5HTR2CALDH1A1 | |
| SCHEMBL14237049 | 0.88 | HTR6 (0.39) | HTR6HTR2CALDH1A1HPGDMAPT | |
| SCHEMBL14237162 | 0.88 | HTR2C (0.37) | HTR6DRD1DRD5HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL1625893 | 0.88 | NPY5R (0.42) | HTR6 | |
| SCHEMBL14237023 | 0.88 | AKR1C3 (0.41) | HTR6DRD1DRD5HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831195-B1 | 5-HT7 RECEPTOR ANTAGONISTS | ESTEVE LABOR DR (ES) | 2012-12-19 | — | — | EP | claimed |