Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.37 |
| ▸ | HTR2B | P41595 | 4/20 | 0.37 |
| ▸ | HTR6 | P50406 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | SGK1 | O00141 | 1/20 | 0.33 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1626880 | 0.99 | HTR2C (0.36) | HTR2CHTR2BHTR6PKMSMN1; SMN2 | |
| SCHEMBL14237022 | 0.90 | HTR2C (0.37) | HTR2CHTR2BL3MBTL1HTR2A | |
| SCHEMBL14237013 | 0.90 | L3MBTL1 (0.36) | HTR6PKMSMN1; SMN2USP30L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1627537 | 0.89 | HTR2C (0.36) | HTR2CHTR2BL3MBTL1HTR2A | |
| Hydrochloric Acid SCHEMBL4894448 | 0.89 | L3MBTL1 (0.36) | HTR6PKMSMN1; SMN2USP30L3MBTL1 | |
| SCHEMBL14237118 | 0.89 | KMT2A (0.35) | HTR6 | |
| SCHEMBL14237115 | 0.88 | HTR6 (0.39) | HTR2CHTR2BHTR6USP30DRD1 | |
| Hydrochloric Acid SCHEMBL1628038 | 0.87 | HTR6 (0.38) | HTR2CHTR2BHTR6USP30DRD1 | |
| SCHEMBL14237116 | 0.87 | HTR6 (0.38) | HTR2CHTR2BHTR6USP30DRD1 | |
| Hydrochloric Acid SCHEMBL1628011 | 0.87 | HTR6 (0.37) | HTR2CHTR2BHTR6USP30HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831195-B1 | 5-HT7 RECEPTOR ANTAGONISTS | ESTEVE LABOR DR (ES) | 2012-12-19 | — | — | EP | claimed |