Triaziquone

SCHEMBL14237183

CC1(C)CC(=O)CC(C)(C)N1O.O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1

nearest known ligand 0.36

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	MAPT	P10636	2/20	0.36

▸	TP53	P04637	1/20	0.36

▸	STAT3	P40763	1/20	0.36

▸	HTT	P42858	1/20	0.36

▸	SMN1; SMN2	Q16637	1/20	0.36

▸	ALDH1A1	P00352	1/20	0.35

▸	DNMT1	P26358	1/20	0.34

▸	HPGD	P15428	1/20	0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Triaziquone SCHEMBL14237202	0.84	TP53 (0.35)	MAPTTP53STAT3HTTSMN1; SMN2
Triaziquone SCHEMBL7783197	0.81	MAPT (0.46)	MAPTTP53STAT3HTTSMN1; SMN2
Triaziquone SCHEMBL2063810	0.79	MAPT (0.44)	MAPTTP53STAT3HTTSMN1; SMN2
Triaziquone SCHEMBL6563614	0.79	MAPT (0.44)	MAPTTP53STAT3HTTSMN1; SMN2
Triaziquone SCHEMBL8303	0.79	DNMT1 (0.48)	MAPTTP53STAT3HTTSMN1; SMN2
Triaziquone SCHEMBL10906735	0.77	HTT (0.43)	MAPTTP53STAT3HTTSMN1; SMN2
Triaziquone SCHEMBL149876	0.77	MAPT (0.46)	MAPTTP53STAT3HTTSMN1; SMN2
Triaziquone SCHEMBL8482641	0.77	DNMT1 (0.47)	MAPTTP53STAT3HTTSMN1; SMN2
Triaziquone SCHEMBL7738777	0.77	DNMT1 (0.47)	MAPTTP53STAT3HTTSMN1; SMN2
Triaziquone SCHEMBL6000230	0.77	DNMT1 (0.47)	MAPTTP53STAT3HTTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1680541-B1	STABILIZED BODY CARE PRODUCTS, HOUSEHOLD PRODUCTS, TEXTILES AND FABRICS	BASF SE (DE)	2012-12-19	—	—	EP	claimed