Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP2 | O95551 | 3/20 | 0.36 |
| ▸ | NSD2 | O96028 | 3/20 | 0.36 |
| ▸ | APAF1 | O14727 | 2/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GALK1 | P51570 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Triaziquone SCHEMBL8303 | 0.92 | DNMT1 (0.48) | MAPTHTTTP53STAT3SMN1; SMN2 | |
| Triaziquone SCHEMBL7783197 | 0.90 | MAPT (0.46) | MAPTHTTTP53STAT3SMN1; SMN2 | |
| Triaziquone SCHEMBL149876 | 0.90 | MAPT (0.46) | MAPTHTTTP53STAT3SMN1; SMN2 | |
| Triaziquone SCHEMBL8482641 | 0.90 | DNMT1 (0.47) | MAPTHTTTP53STAT3SMN1; SMN2 | |
| Triaziquone SCHEMBL1538515 | 0.90 | DNMT1 (0.47) | MAPTHTTTP53STAT3SMN1; SMN2 | |
| Triaziquone SCHEMBL7738777 | 0.90 | DNMT1 (0.47) | MAPTHTTTP53STAT3SMN1; SMN2 | |
| Triaziquone SCHEMBL8993238 | 0.90 | DNMT1 (0.47) | MAPTHTTTP53STAT3SMN1; SMN2 | |
| Triaziquone SCHEMBL6000230 | 0.90 | DNMT1 (0.47) | MAPTHTTTP53STAT3SMN1; SMN2 | |
| Triaziquone SCHEMBL5054475 | 0.90 | DNMT1 (0.47) | MAPTHTTTP53STAT3SMN1; SMN2 | |
| Triaziquone SCHEMBL3101456 | 0.90 | DNMT1 (0.47) | MAPTHTTTP53STAT3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0933993-A4 | SUBSTITUTED CYCLOPENTANE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARM INC (US) | 2004-09-08 | — | — | EP | disclosed |
| EP-0933993-A1 | SUBSTITUTED CYCLOPENTANE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARMACEUTICALS INC. (US) | 1999-08-11 | — | — | EP | disclosed |
| EP-0817642-A1 | $g(b)-SHEET MIMETICS AND USE THEREOF AS INHIBITORS OF BIOLOGICALLY ACTIVE PEPTIDES OR PROTEINS | MOLECUMETICS, LTD. (US) | 1998-01-14 | — | — | EP | disclosed |
| EP-0815123-A1 | $g(b)-SHEET MIMETICS AND USE THEREOF AS PROTEASE INHIBITORS | MOLECUMETICS, LTD. (US) | 1998-01-07 | — | — | EP | disclosed |
| WO-1997047194-A1 | SUBSTITUTED CYCLOPENTANE COMPOUNDS USEFUL AS NEURAMINIDASE INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 1997-12-18 | — | — | WO | disclosed |
| WO-1996030396-A1 | β-SHEET MIMETICS AND USE THEREOF AS PROTEASE INHIBITORS | MOLECUMETICS LTD. (US) | 1996-10-03 | — | — | WO | disclosed |
| WO-1996030035-A1 | β-SHEET MIMETICS AND USE THEREOF AS INHIBITORS OF BIOLOGICALLY ACTIVE PEPTIDES OR PROTEINS | MOLECUMETICS LTD. (US) | 1996-10-03 | — | — | WO | disclosed |