Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Corymbosin SCHEMBL1421623 | 0.90 | MAOB (0.56) | MEN1KMT2AALDH1A1L3MBTL1ABCB1 | |
| SCHEMBL1977048 | 0.88 | ABCB1 (0.59) | MEN1KMT2AL3MBTL1ABCB1TP53 | |
| SCHEMBL1421607 | 0.84 | FLT3 (0.56) | MEN1KMT2AALDH1A1L3MBTL1ABCB1 | |
| SCHEMBL24514601 | 0.82 | ABCB1 (0.73) | MEN1KMT2AALDH1A1L3MBTL1ABCB1 | |
| SCHEMBL24514598 | 0.81 | ABCB1 (0.68) | MEN1KMT2AALDH1A1L3MBTL1ABCB1 | |
| SCHEMBL7156543 | 0.80 | ABCB1 (0.69) | MEN1KMT2AALDH1A1L3MBTL1ABCB1 | |
| SCHEMBL1976409 | 0.80 | CYP1A1 (0.59) | MEN1KMT2AALDH1A1L3MBTL1ABCB1 | |
| SCHEMBL8062100 | 0.79 | MEN1 (0.71) | MEN1KMT2AALDH1A1L3MBTL1ABCB1 | |
| SCHEMBL24514602 | 0.79 | CYP1A1 (0.75) | MEN1KMT2AABCB1TP53MDM2 | |
| SCHEMBL21206267 | 0.78 | ABCB1 (0.73) | MEN1KMT2AALDH1A1ABCB1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2297127-A1 | CHROMENONE DERIVATIVES USEFUL FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | AxoGlia Therapeutics S.A. (LU) | 2011-03-23 | — | — | EP | disclosed |
| WO-2009130253-A1 | CHROMENONE DERIVATIVES USEFUL FOR THE TREATMENT OF NEURODEGENERATIVE DISEASES | AXOGLIA THERAPEUTICS S.A. (LU) | 2009-10-29 | — | — | WO | disclosed |