Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | TP53 | P04637 | 1/20 | 0.73 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.73 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.73 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.62 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7156543 | 0.98 | ABCB1 (0.69) | ABCB1MEN1KMT2ATP53MDM2 | |
| SCHEMBL24514598 | 0.97 | ABCB1 (0.68) | ABCB1MEN1KMT2ATP53MDM2 | |
| SCHEMBL4649969 | 0.96 | ABCB1 (0.73) | ABCB1MEN1KMT2ATP53MDM2 | |
| SCHEMBL8068919 | 0.96 | ABCB1 (0.73) | ABCB1MEN1KMT2ATP53MDM2 | |
| SCHEMBL8052863 | 0.95 | ABCB1 (0.64) | ABCB1MEN1KMT2ATP53MDM2 | |
| SCHEMBL8052929 | 0.94 | ABCB1 (0.69) | ABCB1MEN1KMT2ATP53MDM2 | |
| SCHEMBL21206267 | 0.94 | ABCB1 (0.73) | ABCB1MEN1KMT2ATP53MDM2 | |
| SCHEMBL30376265 | 0.94 | ABCB1 (0.73) | ABCB1MEN1KMT2ATP53MDM2 | |
| SCHEMBL24514602 | 0.92 | CYP1A1 (0.75) | ABCB1MEN1KMT2ATP53MDM2 | |
| SCHEMBL1977048 | 0.91 | ABCB1 (0.59) | ABCB1MEN1KMT2ATP53MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022123573-A1 | COMPOUNDS FOR TREATING EYE DISEASES AND DISORDERS | THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) | 2022-06-16 | — | — | WO | disclosed |