Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 3/20 | 0.70 |
| ▸ | THRB | P10828 | 5/20 | 0.64 |
| ▸ | HPGD | P15428 | 4/20 | 0.64 |
| ▸ | RECQL | P46063 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | BLM | P54132 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | APEX1 | P27695 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.64 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1423903 | 1.00 | PHLPP2 (0.70) | PHLPP2THRBHPGDRECQLALDH1A1 | |
| SCHEMBL1352720 | 0.99 | PHLPP2 (0.69) | PHLPP2THRBHPGDRECQLALDH1A1 | |
| SCHEMBL23787619 | 0.94 | THRB (0.66) | PHLPP2THRBHPGDRECQLALDH1A1 | |
| SCHEMBL19154349 | 0.94 | THRB (0.66) | PHLPP2THRBHPGDRECQLALDH1A1 | |
| SCHEMBL23787721 | 0.93 | PHLPP2 (0.72) | PHLPP2THRBHPGDRECQLALDH1A1 | |
| SCHEMBL1352715 | 0.91 | THRB (0.66) | PHLPP2THRBHPGDRECQLALDH1A1 | |
| SCHEMBL23787576 | 0.85 | THRB (0.64) | PHLPP2THRBHPGDRECQLALDH1A1 | |
| SCHEMBL23787711 | 0.84 | THRB (0.59) | PHLPP2THRBHPGDRECQLALDH1A1 | |
| SCHEMBL12534465 | 0.83 | PHLPP2 (0.54) | PHLPP2THRBHPGDRECQLALDH1A1 | |
| SCHEMBL752770 | 0.83 | THRB (0.69) | PHLPP2THRBHPGDRECQLALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1800151-B1 | LIGHT-POLARIZING SOLID COATING COMPOSITION, OPTICAL LENS COMPRISING SAME, AND METHOD FOR MAKING SAME | ESSILOR INT (FR) | 2011-03-23 | — | — | EP | claimed |