Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 4/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.63 |
| ▸ | RECQL | P46063 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.63 |
| ▸ | APEX1 | P27695 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | MIF | P14174 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.63 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.60 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.58 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29741563 | 1.00 | THRB (0.69) | THRBCYP3A4HPGDMAPK1RECQL | |
| SCHEMBL1352715 | 0.94 | THRB (0.66) | THRBCYP3A4HPGDMAPK1RECQL | |
| SCHEMBL752771 | 0.91 | THRB (0.57) | THRBCYP3A4HPGDMAPK1RECQL | |
| SCHEMBL1435814 | 0.90 | THRB (0.68) | THRBCYP3A4HPGDMAPK1RECQL | |
| SCHEMBL29358163 | 0.90 | THRB (0.68) | THRBCYP3A4HPGDMAPK1RECQL | |
| SCHEMBL23787721 | 0.89 | PHLPP2 (0.72) | THRBCYP3A4HPGDMAPK1RECQL | |
| SCHEMBL29382082 | 0.85 | THRB (0.74) | THRBCYP3A4HPGDMAPK1RECQL | |
| SCHEMBL29637813 | 0.85 | PHLPP2 (0.82) | THRBCYP3A4HPGDMAPK1RECQL | |
| SCHEMBL1423903 | 0.83 | PHLPP2 (0.70) | THRBCYP3A4HPGDMAPK1RECQL | |
| SCHEMBL1423907 | 0.83 | PHLPP2 (0.70) | THRBCYP3A4HPGDMAPK1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6739779-B1 | Fabric repair coloring device and method of using | DEEDS SUZANNE M (US) | 2004-05-25 | — | — | US | claimed |
| US-4025164-A | Liquid crystal display device for colored display of information with a selective polarizer | BBC BROWN BOVERI & COMPANY LIMITED (CH) | 1977-05-24 | — | — | US | claimed |
| EP-3892228-B1 | MEDICAL INSTRUMENT OR PART OF A MEDICAL INSTRUMENT | AESCULAP AG (DE) | 2024-05-08 | — | — | EP | disclosed |
| CN-217188802-U | Nivensic acid production waste gas treatment system | 洛阳和利时环保工程有限公司 | 2022-08-16 | — | — | CN | disclosed |
| EP-3892228-A1 | MEDICAL INSTRUMENT OR PART OF A MEDICAL INSTRUMENT | Aesculap AG (DE) | 2021-10-13 | — | — | EP | disclosed |
| US-9676951-B2 | Ink-jet ink set | SEIKO EPSON CORPORATION (JP) | 2017-06-13 | — | — | US | disclosed |
| US-9573361-B2 | Image-forming method | CANON KABUSHIKI KAISHA (JP) | 2017-02-21 | — | — | US | disclosed |
| US-9353337-B2 | Liquid cleaning composition | THE PROCTER & GAMBLE COMPANY (US) | 2016-05-31 | — | — | US | disclosed |
| EP-2431452-B1 | Liquid cleaning composition | PROCTER & GAMBLE (US) | 2015-07-08 | — | — | EP | disclosed |
| US-20140345494-A1 | INK-JET INK SET | SEIKO EPSON CORPORATION (JP) | 2014-11-27 | — | — | US | disclosed |
| US-20130088543-A1 | IMAGE-FORMING METHOD | CANON KABUSHIKI KAISHA (JP) | 2013-04-11 | — | — | US | disclosed |
| WO-1998030642-A1 | METHODS FOR IMPROVING THE ADHESION AND/OR COLORFASTNESS OF INK JET INKS WITH RESPECT TO SUBSTRATES APPLIED THERETO, AND COMPOSITIONS USEFUL THEREFOR | FORMULABS (US) | 1998-07-16 | — | — | WO | disclosed |
| EP-0838508-A2 | Aqueous ink composition for use in an ink-jet printer | SEIKO EPSON CORPORATION (JP) | 1998-04-29 | — | — | EP | disclosed |
| EP-0825029-A2 | Printer and printing method | SONY CORPORATION (JP) | 1998-02-25 | — | — | EP | disclosed |
| US-5529617-A | MIXTURE OF WATER, COLORING MATERIAL, HIGH MOLECULAR WEIGHT SURFACTANT AND SULFUR CONTAINING ALCOHOL | FUJI XEROX CO., LTD. (JP) | 1996-06-25 | — | — | US | disclosed |
| EP-0633914-A1 | PENETRANTS FOR AQUEOUS INK JET INKS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-01-18 | — | — | EP | disclosed |
| WO-1992022614-A1 | PENETRANTS FOR AQUEOUS INK JET INKS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-12-23 | — | — | WO | disclosed |
| US-5141556-A | Branched diols or hexene-1,2-diols along with a pigment or dye; rapid drying; storage stability; quality; thermal printers | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-08-25 | — | — | US | disclosed |
| US-4604337-A | Electrophotographic color copying paper and copying method making use of the same | OLYMPUS OPTICAL CO., LTD. (JP) | 1986-08-05 | — | — | US | disclosed |
| US-4365998-A | Aqueous inks for ink jet printing | FUJI PHOTO FILM CO., LTD. (JP) | 1982-12-28 | — | — | US | disclosed |