Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3885999 | 0.82 | EPHX1 (0.44) | ALDH1A1TDP1POLBTHRBATM | |
| SCHEMBL11493993 | 0.78 | KMT2A (0.47) | ALDH1A1TDP1SMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4725324 | 0.76 | ALDH1A1 (0.42) | ALDH1A1POLBTSHRSMN1; SMN2HPGD | |
| SCHEMBL3946457 | 0.76 | ALDH1A1 (0.42) | ALDH1A1POLBTSHRTHRBATM | |
| SCHEMBL9127774 | 0.76 | KMT2A (0.48) | ALDH1A1TDP1L3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL8656457 | 0.75 | KMT2A (0.41) | ALDH1A1POLBTSHRSMN1; SMN2HPGD | |
| SCHEMBL4845577 | 0.74 | ALDH1A1 (0.39) | ALDH1A1POLBTSHRSMN1; SMN2HPGD | |
| SCHEMBL21066382 | 0.74 | ALDH1A1 (0.39) | ALDH1A1POLBTSHRATMSMN1; SMN2 | |
| SCHEMBL20600234 | 0.73 | ALDH1A1 (0.40) | ALDH1A1TDP1POLBTSHRTHRB | |
| SCHEMBL20599579 | 0.73 | ALDH1A1 (0.40) | ALDH1A1TDP1POLBTSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2297114-A2 | HETEROCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2011-03-23 | — | — | EP | disclosed |