Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 4/20 | 0.40 |
| ▸ | PTK2 | Q05397 | 4/20 | 0.40 |
| ▸ | JAK2 | O60674 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15641297 | 1.00 | NAMPT (0.43) | NAMPTWNT3ADDB1CRBNALK | |
| SCHEMBL14240396 | 0.85 | DDB1 (0.45) | NAMPTWNT3ADDB1CRBNALK | |
| SCHEMBL15641277 | 0.84 | DDB1 (0.46) | NAMPTWNT3ADDB1CRBNALK | |
| SCHEMBL14240418 | 0.82 | ALK (0.46) | NAMPTWNT3ADDB1CRBNALK | |
| SCHEMBL14239643 | 0.80 | KDR (0.46) | WNT3ADDB1CRBNHPGDSGPR119 | |
| SCHEMBL14240527 | 0.80 | DDB1 (0.45) | WNT3ADDB1CRBNALKJAK3 | |
| SCHEMBL15641241 | 0.79 | ABL1 (0.49) | — | |
| SCHEMBL14240654 | 0.79 | ABL1 (0.49) | — | |
| SCHEMBL14240395 | 0.79 | PKMYT1 (0.47) | NAMPTWNT3AALKMAPTLMNA | |
| SCHEMBL14240653 | 0.79 | WNT3A (0.45) | WNT3ADDB1CRBNALKJAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2719696-A1 | NOVEL KINASE INHIBITORS | Asinex Limited (RU) | 2014-04-16 | — | — | EP | disclosed |
| WO-2012169934-A1 | NOVEL KINASE INHIBITORS | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "АСИНЭКС МЕДХИМ" (RU) | 2012-12-13 | — | — | WO | disclosed |