Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14240527 | 0.93 | DDB1 (0.45) | KDRTP53SYKDDB1CRBN | |
| SCHEMBL14240653 | 0.90 | WNT3A (0.45) | KDRSYKDDB1CRBNWNT3A | |
| SCHEMBL14240418 | 0.89 | ALK (0.46) | KDRTP53SYKDDB1CRBN | |
| SCHEMBL15641277 | 0.84 | DDB1 (0.46) | SYKDDB1CRBNWNT3AGPR119 | |
| SCHEMBL14240396 | 0.83 | DDB1 (0.45) | SYKDDB1CRBNWNT3AGPR119 | |
| SCHEMBL15641367 | 0.81 | KDR (0.51) | KDRTP53SYKWNT3ACHEK1 | |
| SCHEMBL14239640 | 0.80 | SRC (0.49) | KDRCHEK1 | |
| SCHEMBL14239679 | 0.80 | NAMPT (0.43) | SYKDDB1CRBNWNT3AGPR119 | |
| SCHEMBL15641297 | 0.80 | NAMPT (0.43) | SYKDDB1CRBNWNT3AGPR119 | |
| SCHEMBL14240508 | 0.79 | MMP13 (0.46) | KDRGPR119HPGDSMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012169934-A1 | NOVEL KINASE INHIBITORS | ОБЩЕСТВО С ОГРАНИЧЕННОЙ ОТВЕТСТВЕННОСТЬЮ "АСИНЭКС МЕДХИМ" (RU) | 2012-12-13 | — | — | WO | disclosed |