Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.90 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3475010 | 1.00 | CHRNA7 (0.90) | CHRNA7TAAR1TSHROPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL7516224 | 0.98 | CHRNA7 (0.87) | CHRNA7TAAR1TSHROPRM1OPRK1 | |
| SCHEMBL2811534 | 0.95 | CHRNA7 (1.00) | CHRNA7TAAR1OPRM1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL7509300 | 0.93 | CHRNA7 (0.96) | CHRNA7TAAR1OPRM1OPRK1OPRL1 | |
| Iodide SCHEMBL7016592 | 0.93 | CHRNA7 (0.96) | CHRNA7TAAR1OPRM1OPRK1OPRL1 | |
| SCHEMBL5899579 | 0.91 | CHRNA7 (0.80) | CHRNA7TAAR1TSHROPRM1OPRK1 | |
| SCHEMBL20137193 | 0.91 | CHRNA7 (0.80) | CHRNA7TAAR1TSHROPRM1OPRK1 | |
| SCHEMBL9737757 | 0.89 | CHRNA7 (0.77) | CHRNA7TAAR1TSHROPRM1OPRK1 | |
| SCHEMBL5264779 | 0.89 | CHRNA7 (0.77) | CHRNA7TAAR1TSHROPRM1OPRK1 | |
| SCHEMBL10753534 | 0.89 | CHRNA7 (0.82) | CHRNA7TAAR1OPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012168368-A1 | BENZOQUINOLIZIDINE DERIVATIVES, METHOD FOR PREPARING SAME, AND THERAPEUTIC USES THEREOF | PIERRE FABRE MEDICAMENT (FR) | 2012-12-13 | — | — | WO | disclosed |