SCHEMBL14240481

SCHEMBL14240481

COC(=O)CNCCC(=O)Nc1cccc2c1C(=O)c1cccc(NC(=O)CCNCC(=O)OC)c1C2=O

nearest known ligand 0.62

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.62
PTPN13 Q12923 1/20 0.62
TERT O14746 13/20 0.60
MEN1 O00255 1/20 0.52
ALDH1A1 P00352 1/20 0.52
POLB P06746 1/20 0.52
GAA P10253 1/20 0.52
MAPT P10636 1/20 0.52
DNMT1 P26358 1/20 0.52
RAD52 P43351 1/20 0.52
SMARCA2 P51531 1/20 0.52
KMT2A Q03164 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14240479 0.90 PTPRC (0.62) PTPRCPTPN13TERTMEN1ALDH1A1
SCHEMBL14239612 0.90 PTPRC (0.58) PTPRCPTPN13TERTMEN1ALDH1A1
SCHEMBL12110437 0.84 TERT (0.58) PTPRCPTPN13TERTMEN1ALDH1A1
SCHEMBL9510413 0.78 TERT (0.73) PTPRCPTPN13TERTMEN1ALDH1A1
SCHEMBL14239609 0.77 PTPRC (0.55) PTPRCPTPN13TERTMEN1ALDH1A1
SCHEMBL1304372 0.77 TERT (0.62) PTPRCPTPN13TERTMEN1ALDH1A1
SCHEMBL12110708 0.77 TERT (0.70) PTPRCPTPN13TERTMEN1ALDH1A1
SCHEMBL6258519 0.76 PTPRC (0.85) PTPRCPTPN13TERTMEN1ALDH1A1
SCHEMBL6263283 0.76 PTPRC (1.00) PTPRCPTPN13TERTMEN1ALDH1A1
SCHEMBL12110694 0.76 TERT (0.81) PTPRCPTPN13TERTMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120316234-A1 ANTHRAQUINONE -BASED COMPOUND, THE SYNTHESIS PROCESSES AND THE APPLICATION THEREOF NATIONAL DEFENSE MEDICAL CENTER (TW) 2012-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120316234-A1 ANTHRAQUINONE -BASED COMPOUND, THE SYNTHESIS PROCESSES AND THE APPLICATION THEREOF AAAS, QPCT, NQO2 PTPRC 4400/4885PTPN13 4825/4885TERT 2376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.