Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 6/20 | 1.00 |
| ▸ | PTPN13 | Q12923 | 3/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | TERT | O14746 | 8/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.54 |
| ▸ | RAD52 | P43351 | 1/20 | 0.54 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6258519 | 0.92 | PTPRC (0.85) | PTPRCPTPN13ALDH1A1POLBCYP1A2 | |
| SCHEMBL6264027 | 0.84 | PTPRC (0.73) | PTPRCPTPN13ALDH1A1POLBCYP1A2 | |
| SCHEMBL6259066 | 0.83 | PTPRC (0.71) | PTPRCPTPN13ALDH1A1POLBCYP1A2 | |
| SCHEMBL6263526 | 0.83 | PTPRC (0.71) | PTPRCPTPN13ALDH1A1POLBCYP1A2 | |
| SCHEMBL6261141 | 0.80 | PTPRC (0.73) | PTPRCPTPN13ALDH1A1POLBCYP1A2 | |
| SCHEMBL6261316 | 0.78 | PTPRC (1.00) | PTPRCPTPN13ALDH1A1POLBCYP1A2 | |
| SCHEMBL6260674 | 0.78 | PTPRC (0.95) | PTPRCPTPN13ALDH1A1POLBCYP1A2 | |
| SCHEMBL11656337 | 0.78 | MAOA (0.64) | PTPRCPTPN13ALDH1A1POLBTERT | |
| SCHEMBL14240479 | 0.76 | PTPRC (0.62) | PTPRCPTPN13ALDH1A1POLBTERT | |
| SCHEMBL14240481 | 0.76 | PTPRC (0.62) | PTPRCPTPN13ALDH1A1POLBTERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242363-B1 | CD45 INHIBITORS | ASTRAZENECA AB (SE) | 2005-11-02 | — | — | EP | disclosed |
| US-20030207812-A1 | Cd45 inhibitors | ASTRAZENECA AB (SE) | 2003-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207812-A1 | Cd45 inhibitors | CD74, CD2, PTPRC | PTPRC 3/4885PTPN13 69/4885ALDH1A1 2578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.