Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.58 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.53 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.52 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.52 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.52 |
| ▸ | CPB1 | P15086 | 1/20 | 0.51 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.51 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.51 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15084866 | 0.96 | SIRT2 (0.61) | SIRT2SIRT1FOLH1SIRT3CAPN1 | |
| SCHEMBL22055423 | 0.95 | SIRT2 (0.63) | SIRT2SIRT1FOLH1SIRT3CAPN1 | |
| SCHEMBL15084702 | 0.94 | SIRT2 (0.59) | SIRT2SIRT1FOLH1SIRT3CAPN1 | |
| SCHEMBL14642695 | 0.92 | SIRT2 (0.64) | SIRT2SIRT1SIRT3CAPN1CAPN2 | |
| SCHEMBL14642694 | 0.92 | SIRT2 (0.59) | SIRT2SIRT1FOLH1SIRT3CAPN1 | |
| SCHEMBL20980386 | 0.91 | CPB1 (0.60) | SIRT2SIRT1FOLH1SIRT3CPB1 | |
| SCHEMBL14642785 | 0.90 | SIRT2 (0.57) | SIRT2SIRT1FOLH1SIRT3CAPN1 | |
| SCHEMBL14642700 | 0.90 | SIRT2 (0.57) | SIRT2SIRT1FOLH1SIRT3CAPN1 | |
| SCHEMBL14642788 | 0.90 | SIRT2 (0.62) | SIRT2SIRT1SIRT3CAPN1CAPN2 | |
| SCHEMBL18653805 | 0.90 | SIRT2 (0.57) | SIRT2SIRT1SIRT3CAPN1CAPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012170952-A2 | COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING SIRNA ACTIVITY | NITTO DENKO CORPORATION (JP) | 2012-12-13 | — | — | WO | disclosed |