Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.59 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.54 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.54 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.54 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.54 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.53 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.53 |
| ▸ | CPB1 | P15086 | 1/20 | 0.53 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15084866 | 0.98 | SIRT2 (0.61) | SIRT2SIRT1SIRT5PTGER4FOLH1 | |
| SCHEMBL22055423 | 0.97 | SIRT2 (0.63) | SIRT2SIRT1PTGER4FOLH1SIRT3 | |
| SCHEMBL14642700 | 0.96 | SIRT2 (0.57) | SIRT2SIRT1SIRT5PTGER4FOLH1 | |
| SCHEMBL14642785 | 0.96 | SIRT2 (0.57) | SIRT2SIRT1SIRT5PTGER4FOLH1 | |
| SCHEMBL14642788 | 0.96 | SIRT2 (0.62) | SIRT2SIRT1SIRT3CAPN1CAPN2 | |
| SCHEMBL18653805 | 0.95 | SIRT2 (0.57) | SIRT2SIRT1SIRT5PTGER4SIRT3 | |
| SCHEMBL14240585 | 0.94 | SIRT2 (0.58) | SIRT2SIRT1SIRT5PTGER4FOLH1 | |
| SCHEMBL14642695 | 0.94 | SIRT2 (0.64) | SIRT2SIRT1SIRT3CAPN1CAPN2 | |
| SCHEMBL14642694 | 0.94 | SIRT2 (0.59) | SIRT2SIRT1FOLH1SIRT3CAPN1 | |
| SCHEMBL15084738 | 0.93 | SIRT2 (0.53) | SIRT2SIRT1SIRT5PTGER4FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170000893-A1 | COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING siRNA ACTIVITY | NITTO DENKO CORP (JP) | 2017-01-05 | — | — | US | disclosed |
| US-20170001950-A1 | COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING siRNA ACTIVITY | NITTO DENKO CORP (JP) | 2017-01-05 | — | — | US | disclosed |
| US-20130210744-A1 | TARGETING AGENT FOR CANCER CELL OR CANCER-ASSOCIATED FIBROBLAST | NITTO DENKO CORPORATION (JP) | 2013-08-15 | — | — | US | disclosed |
| US-20130171240-A1 | DRUG CARRIER AND DRUG CARRIER KIT FOR INHIBITING FIBROSIS | NITTO DENKO CORPORATION (JP) | 2013-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130171240-A1 | DRUG CARRIER AND DRUG CARRIER KIT FOR INHIBITING FIBROSIS | KIT, STRA6, HAVCR2 | SIRT2 1708/4885SIRT1 1340/4885SIRT5 3096/4885 |
| US-20170001950-A1 | COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING siRNA ACTIVITY | LDLR, RARG, FABP4 | SIRT2 2436/4885SIRT1 1811/4885SIRT5 3501/4885 |
| US-20170000893-A1 | COMPOUNDS FOR TARGETING DRUG DELIVERY AND ENHANCING siRNA ACTIVITY | LDLR, RARG, FABP4 | SIRT2 2436/4885SIRT1 1811/4885SIRT5 3501/4885 |
| US-20130210744-A1 | TARGETING AGENT FOR CANCER CELL OR CANCER-ASSOCIATED FIBROBLAST | FGFR2, FRS2, FOLR1 | SIRT2 2950/4885SIRT1 2979/4885SIRT5 3701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.