Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2B | P67870 | 3/20 | 0.44 |
| ▸ | ITK | Q08881 | 4/20 | 0.42 |
| ▸ | LCK | P06239 | 3/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 6/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.38 |
| ▸ | TYK2 | P29597 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14243301 | 0.82 | CSNK2B (0.48) | CSNK2BCSNK2A2CSNK2A1TYK2KCNH2 | |
| SCHEMBL14242544 | 0.80 | CSNK2B (0.51) | CSNK2BCSNK2A2CSNK2A1TYK2KCNH2 | |
| SCHEMBL14243294 | 0.79 | CSNK2B (0.45) | CSNK2BCSNK2A2CSNK2A1TYK2KCNH2 | |
| SCHEMBL14243124 | 0.79 | CSNK2B (0.48) | CSNK2BCSNK2A2CSNK2A1TYK2KCNH2 | |
| SCHEMBL14242464 | 0.76 | CSNK2B (0.44) | CSNK2BCSNK2A2CSNK2A1TYK2KCNH2 | |
| SCHEMBL14242596 | 0.76 | CSNK2B (0.40) | CSNK2BCSNK2A2CSNK2A1TYK2KCNH2 | |
| SCHEMBL12583367 | 0.76 | CSNK2B (0.43) | CSNK2BITKLCKAURKBCSNK2A2 | |
| SCHEMBL15368253 | 0.75 | ITK (0.43) | CSNK2BITKLCKAURKBCSNK2A2 | |
| SCHEMBL12583272 | 0.74 | CSNK2B (0.59) | CSNK2BITKLCKAURKBMEN1 | |
| SCHEMBL14242893 | 0.74 | CSNK2B (0.40) | CSNK2BCSNK2A2CSNK2A1TYK2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012170827-A2 | PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS | CYLENE PHARMACEUTICALS, INC. (US) | 2012-12-13 | — | — | WO | disclosed |