Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2B | P67870 | 3/20 | 0.48 |
| ▸ | BCL6 | P41182 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 11/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 3/20 | 0.32 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | CCNH | P51946 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | CDK3 | Q00526 | 1/20 | 0.32 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14242464 | 0.86 | CSNK2B (0.44) | CSNK2BBCL6KCNH2CSNK2A1CSNK2A2 | |
| SCHEMBL14242544 | 0.86 | CSNK2B (0.51) | CSNK2BBCL6KCNH2CSNK2A1CSNK2A2 | |
| SCHEMBL14243301 | 0.84 | CSNK2B (0.48) | CSNK2BKCNH2CSNK2A1CSNK2A2TYK2 | |
| SCHEMBL14242542 | 0.82 | CSNK2B (0.40) | CSNK2BBCL6CSNK2A1 | |
| SCHEMBL2028655 | 0.81 | CSNK2B (0.69) | CSNK2BBCL6CSNK2A1CSNK2A2CDK2 | |
| SCHEMBL14242545 | 0.81 | CSNK2A1 (0.41) | CSNK2BBCL6KCNH2CSNK2A1CSNK2A2 | |
| SCHEMBL14243294 | 0.80 | CSNK2B (0.45) | CSNK2BKCNH2CSNK2A1CSNK2A2TYK2 | |
| SCHEMBL14242539 | 0.79 | CSNK2B (0.44) | CSNK2BKCNH2CSNK2A1CSNK2A2TYK2 | |
| SCHEMBL14242540 | 0.78 | CSNK2B (0.37) | CSNK2BCSNK2A1CSNK2A2TYK2CCNT1 | |
| SCHEMBL14242596 | 0.77 | CSNK2B (0.40) | CSNK2BKCNH2CSNK2A1CSNK2A2TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012170827-A2 | PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS | CYLENE PHARMACEUTICALS, INC. (US) | 2012-12-13 | — | — | WO | disclosed |