Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 7/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.39 |
| ▸ | BCL6 | P41182 | 2/20 | 0.34 |
| ▸ | TYK2 | P29597 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TTK | P33981 | 2/20 | 0.32 |
| ▸ | CDK2 | P24941 | 2/20 | 0.32 |
| ▸ | GSK3B | P49841 | 2/20 | 0.32 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.32 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.32 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14243124 | 0.81 | CSNK2B (0.48) | CSNK2A1CSNK2BBCL6TYK2KCNH2 | |
| SCHEMBL14243408 | 0.77 | CSNK2B (0.41) | CSNK2A1CSNK2BBCL6TYK2MEN1 | |
| SCHEMBL14242544 | 0.76 | CSNK2B (0.51) | CSNK2A1CSNK2BBCL6TYK2KCNH2 | |
| SCHEMBL14242464 | 0.76 | CSNK2B (0.44) | CSNK2A1CSNK2BBCL6TYK2KCNH2 | |
| SCHEMBL14242540 | 0.76 | CSNK2B (0.37) | CSNK2A1CSNK2BTYK2CCNT1CDK9 | |
| SCHEMBL19527149 | 0.75 | MLNR (0.38) | CSNK2B | |
| SCHEMBL14243301 | 0.74 | CSNK2B (0.48) | CSNK2A1CSNK2BTYK2KCNH2CDK2 | |
| SCHEMBL14242542 | 0.74 | CSNK2B (0.40) | CSNK2A1CSNK2BBCL6 | |
| SCHEMBL14243294 | 0.73 | CSNK2B (0.45) | CSNK2A1CSNK2BTYK2KCNH2MEN1 | |
| SCHEMBL19526918 | 0.72 | CSNK2B (0.40) | CSNK2A1CSNK2BBCL6TYK2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012170827-A2 | PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS | CYLENE PHARMACEUTICALS, INC. (US) | 2012-12-13 | — | — | WO | disclosed |