Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2B | P67870 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 2/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14243124 | 0.78 | CSNK2B (0.48) | CSNK2BCSNK2A1TYK2CCNT1CDK9 | |
| SCHEMBL18405391 | 0.78 | CSNK2B (0.35) | CSNK2BMTNR1AMTNR1BCSNK2A1MCHR1 | |
| SCHEMBL12644496 | 0.77 | POLB (0.39) | CSNK2BMTNR1AMTNR1BCSNK2A1MCHR1 | |
| SCHEMBL19526952 | 0.77 | ADORA2A (0.36) | CSNK2BMTNR1AMTNR1BCSNK2A1MCHR1 | |
| SCHEMBL14242545 | 0.76 | CSNK2A1 (0.41) | CSNK2BCSNK2A1TYK2CCNT1CDK9 | |
| SCHEMBL14243294 | 0.74 | CSNK2B (0.45) | CSNK2BCSNK2A1TYK2MEN1NPC1 | |
| SCHEMBL14243301 | 0.73 | CSNK2B (0.48) | CSNK2BCSNK2A1TYK2PDE4DCSNK2A2 | |
| SCHEMBL14242539 | 0.71 | CSNK2B (0.44) | CSNK2BCSNK2A1TYK2MEN1NPC1 | |
| SCHEMBL14242542 | 0.70 | CSNK2B (0.40) | CSNK2BCSNK2A1 | |
| SCHEMBL19527149 | 0.69 | MLNR (0.38) | CSNK2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012170827-A2 | PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS | CYLENE PHARMACEUTICALS, INC. (US) | 2012-12-13 | — | — | WO | disclosed |