SCHEMBL14243308

SCHEMBL14243308

CC1=CCC(c2cc(N(C(=O)OC(C)(C)C)C(C)C)n3ncc(C=O)c3n2)S1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CSNK2B P67870 1/20 0.31
USP30 Q70CQ3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14242903 0.89 CSNK2B (0.32) CSNK2B
SCHEMBL14243313 0.82 CCNT1 (0.34) USP30
SCHEMBL14242528 0.80 CSNK2B (0.38) CSNK2B
SCHEMBL14243147 0.77 CSNK2B (0.31) CSNK2B
SCHEMBL14243322 0.77 CSNK2B (0.31) CSNK2B
SCHEMBL14243320 0.73 CSNK2B (0.32) CSNK2B
SCHEMBL14242905 0.72 CSNK2B (0.42) CSNK2B
SCHEMBL14243307 0.70 PAX8 (0.32)
SCHEMBL12645224 0.67 CSNK2B (0.32) CSNK2B
SCHEMBL1487758 0.66 CSNK2B (0.37) CSNK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012170827-A2 PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS CYLENE PHARMACEUTICALS, INC. (US) 2012-12-13 WO disclosed