SCHEMBL142445

SCHEMBL142445

O=C(OCc1ccccc1)ON1C(=O)CCC1=O

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.47
L3MBTL1 Q9Y468 2/20 0.46
KMT2A Q03164 2/20 0.46
MAPK1 P28482 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A3 Q01959 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
CCNE1 P24864 1/20 0.45
CDK2 P24941 1/20 0.45
GSK3B P49841 1/20 0.45
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
DDB1 Q16531 1/20 0.43
CRBN Q96SW2 1/20 0.43
MEN1 O00255 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
PKM P14618 1/20 0.43
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11323517 1.00 ALDH1A1 (0.47) ALDH1A1L3MBTL1KMT2AMAPK1SLC6A2
SCHEMBL1279658 0.98 ALDH1A1 (0.46) ALDH1A1L3MBTL1KMT2AMAPK1SLC6A2
Carbamic Acid SCHEMBL28871401 0.95 CYP2C19 (0.44) ALDH1A1L3MBTL1KMT2AMAPK1SLC6A2
SCHEMBL6363978 0.93 CCNE1 (0.42) ALDH1A1L3MBTL1KMT2AMAPK1SLC6A2
SCHEMBL9942943 0.90 ALDH1A1 (0.41) ALDH1A1L3MBTL1KMT2AMAPK1SLC6A2
SCHEMBL5469498 0.90 ALDH1A1 (0.47) ALDH1A1L3MBTL1KMT2AMAPK1SLC6A2
SCHEMBL15999210 0.87 NOTUM (0.51) ALDH1A1L3MBTL1KMT2AMAPK1SLC6A2
SCHEMBL406279 0.87 KMT2A (0.41) ALDH1A1L3MBTL1KMT2AMAPK1SLC6A2
SCHEMBL5963233 0.86 CA2 (0.43) ALDH1A1L3MBTL1KMT2AMAPK1CCNE1
SCHEMBL19763139 0.86 ALDH1A1 (0.50) ALDH1A1L3MBTL1KMT2AMAPK1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4833 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122036924-A Synthetic method of bionic collagen hexapeptide 成都欣肽生物科技有限公司 2026-05-15 CN claimed
CN-119350189-A Method for preparing N-methyl-N-benzyloxycarbonyl-L-aspartic acid-4-tert-butyl ester 上海农林职业技术学院 2025-01-24 CN claimed
CN-118791403-A Refining method of compound intermediate containing gamma-glutamyl transpeptidase response motif 安徽普利药业有限公司 2024-10-18 CN claimed
CN-118084735-A Photo-delay synthesis method of O- [2- [ [ tert-butyloxycarbonyl ] amino ] ethyl ] -N- [ fluorenylmethoxycarbonyl ] -L-tyrosine 吉尔多肽生物制药(大连市)有限公司 2024-05-28 CN claimed
CN-118005554-A Synthesis method of 5, 6-dihydroxyindole and intermediate thereof 北京颖诺凯胜科技有限公司 2024-05-10 CN claimed
CN-117924113-A AEEA-AEEA synthesis method 成都普康唯新生物科技有限公司 2024-04-26 CN claimed
CN-117820136-A Synthesis method of 2- (2- (2-amino ethoxy) acetic acid 康羽生命科学技术(苏州)有限公司 2024-04-05 CN claimed
CN-114105848-B Preparation method of cis-D-hydroxyproline derivative 四川同晟生物医药有限公司 2024-01-12 CN claimed
US-11799085-B2 Method of manufacturing negative electrode for lithium secondary battery and lithium secondary battery LG ENERGY SOLUTION, LTD. (KR) 2023-10-24 US claimed
US-11788080-B2 Modified cleavases, uses thereof and related kits Encodia, Inc. (US) 2023-10-17 US claimed
US-5621085-A Process for the preparation of amikacin precursors BIOCHIMICA OPOS S.P.A. (IT) 1997-04-15 US claimed
US-5426190-A Preparation of N-(organocarbonyloxy)-succinimide derivatives of N-hydroxysuccinimide PPG INDUSTRIES, INC. (US) 1995-06-20 US claimed
EP-0446798-B1 1-alkyl-, 1-alkenyl- and 1-alkynylaryl-2-amino-1, 3-propanediols and related compounds, a process and intermediates for their preparation and their use as medicaments HOECHST ROUSSEL PHARMA (US) 1994-11-23 EP claimed
EP-0446670-B1 Method of preparation of amikacin precursors OPOS BIOCHIMICA SRL (IT) 1994-09-21 EP claimed
EP-0446798-A1 1-alkyl-, 1-alkenyl- and 1-alkynylaryl-2-amino-1, 3-propanediols and related compounds, a process and intermediates for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1991-09-18 EP claimed
EP-0446670-A1 Method of preparation of amikacin precursors BIOCHIMICA OPOS SPA (IT) 1991-09-18 EP claimed
US-4231924-A ACYLATION, HYDROLYSIS ABBOTT LABORATORIES (US) 1980-11-04 US claimed
US-4169941-A ANTIBIOTICS, URETHANE-TYPE AMINO PROTECTION REACTION ABBOTT LABORATORIES (US) 1979-10-02 US claimed
US-4155902-A ACYLATION, HYDROGENOLYSIS ABBOTT LABORATORIES (US) 1979-05-22 US claimed
US-4124756-A REACTION WITH PROTECTED AMINO ACIDS TO FORM 3-DE-O-METHYL-N-ACYLFORTIMICINS; ANTIBACTERIAL ABBOTT LABORATORIES (US) 1978-11-07 US claimed