Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.44 |
| ▸ | KDM1A | O60341 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3997126 | 0.86 | AAK1 (0.46) | AAK1HDAC1HDAC2 | |
| SCHEMBL14247658 | 0.79 | PKM (0.46) | PRSS1 | |
| SCHEMBL20641725 | 0.78 | NCF1 (0.39) | KDM1AMAOAMAOBHDAC1HDAC2 | |
| SCHEMBL30437635 | 0.78 | NCF1 (0.39) | KDM1AMAOAMAOBHDAC1HDAC2 | |
| SCHEMBL14905734 | 0.76 | PRKCQ (0.38) | KDM1AMAOAMAOBCHRM2CHRM1 | |
| SCHEMBL18172298 | 0.76 | JAK3 (0.38) | KDM1AMAOAMAOBCHRM2CHRM1 | |
| SCHEMBL2942637 | 0.75 | AAK1 (0.48) | AAK1 | |
| SCHEMBL2687892 | 0.75 | AAK1 (0.44) | AAK1KDM1AMAOAMAOB | |
| SCHEMBL29791971 | 0.75 | AAK1 (0.44) | AAK1KDM1AMAOAMAOB | |
| SCHEMBL16035266 | 0.74 | PTGER4 (0.41) | AAK1HDAC1HDAC2PIM1PIM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012174312-A2 | BENZIMIDAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-12-20 | — | — | WO | disclosed |
| WO-2012174312-A2 | BENZIMIDAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-12-20 | — | — | WO | disclosed |