Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18732123 | 0.84 | PKM (0.46) | KMT2APOLBCYP1A2TERTNQO2 | |
| SCHEMBL14247443 | 0.81 | KMT2A (0.47) | TLR8KMT2APOLBCXCR4CYP1A2 | |
| SCHEMBL14247515 | 0.81 | KMT2A (0.47) | TLR8KMT2APOLBCXCR4CYP1A2 | |
| Hydrochloric Acid SCHEMBL14247462 | 0.79 | KMT2A (0.46) | TLR8KMT2APOLBCXCR4CYP1A2 | |
| SCHEMBL6930946 | 0.79 | POLB (0.69) | TLR8KMT2APOLBCXCR4CYP1A2 | |
| SCHEMBL14247313 | 0.78 | TLR8 (0.51) | TLR8KMT2APOLBCXCR4CYP1A2 | |
| SCHEMBL14247241 | 0.78 | BACE1 (0.58) | TLR8KMT2APOLBCXCR4CYP1A2 | |
| Hydrochloric Acid SCHEMBL6934113 | 0.78 | POLB (0.67) | TLR8KMT2APOLBCXCR4CYP1A2 | |
| SCHEMBL14247585 | 0.77 | HTR7 (0.49) | TLR8KMT2APOLBCXCR4HTT | |
| SCHEMBL989394 | 0.77 | DYRK3 (0.46) | TLR8KMT2APOLBCXCR4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012174312-A2 | BENZIMIDAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-12-20 | — | — | WO | disclosed |
| WO-2012174312-A2 | BENZIMIDAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-12-20 | — | — | WO | disclosed |