Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.48 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14247313 | 0.82 | TLR8 (0.51) | TLR8CXCR4KMT2ABACE1NUDT1 | |
| SCHEMBL14247241 | 0.82 | BACE1 (0.58) | TLR8CXCR4KMT2ABACE1NUDT1 | |
| SCHEMBL14247443 | 0.79 | KMT2A (0.47) | TLR8CXCR4KMT2ABACE1NUDT1 | |
| SCHEMBL14247515 | 0.79 | KMT2A (0.47) | TLR8CXCR4KMT2ABACE1NUDT1 | |
| SCHEMBL14247558 | 0.77 | CXCR4 (0.52) | TLR8CXCR4KMT2ABACE1POLB | |
| Hydrochloric Acid SCHEMBL14247462 | 0.77 | KMT2A (0.46) | TLR8CXCR4KMT2ABACE1NUDT1 | |
| SCHEMBL14247506 | 0.76 | TLR8 (0.46) | TLR8CXCR4KMT2ABACE1NUDT1 | |
| SCHEMBL14247624 | 0.75 | TLR8 (0.47) | TLR8CXCR4KMT2ABACE1POLB | |
| SCHEMBL14247207 | 0.74 | ALOX15 (0.47) | TLR8CXCR4KMT2ALMNAHSD17B10 | |
| SCHEMBL14247475 | 0.74 | TLR8 (0.44) | TLR8CXCR4KMT2ABACE1NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012174312-A2 | BENZIMIDAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-12-20 | — | — | WO | disclosed |
| WO-2012174312-A2 | BENZIMIDAZOLE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-12-20 | — | — | WO | disclosed |