Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.47 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenyl Propionic Acid SCHEMBL7409966 | 0.89 | KEAP1 (0.66) | FFAR1KEAP1ALDH1A1FFAR4 | |
| SCHEMBL879572 | 0.85 | ALDH1A1 (0.59) | FFAR1KEAP1CA1CA2NPSR1 | |
| SCHEMBL7285127 | 0.83 | S1PR1 (0.50) | FFAR1KEAP1CA1CA2NPSR1 | |
| SCHEMBL11482669 | 0.83 | TAAR1 (0.57) | FFAR1KEAP1CA1CA2NPSR1 | |
| SCHEMBL27604134 | 0.83 | FFAR1 (0.57) | FFAR1KEAP1CA1CA2NPSR1 | |
| SCHEMBL10429887 | 0.83 | TAAR1 (0.57) | FFAR1KEAP1CA1CA2NPSR1 | |
| SCHEMBL29009990 | 0.81 | FFAR1 (0.55) | FFAR1KEAP1CA1CA2NPSR1 | |
| SCHEMBL27649243 | 0.81 | FFAR1 (0.55) | FFAR1KEAP1CA1CA2NPSR1 | |
| SCHEMBL29010119 | 0.81 | FFAR1 (0.55) | FFAR1KEAP1CA1CA2NPSR1 | |
| SCHEMBL11795064 | 0.81 | F2 (0.56) | FFAR1CA2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718299-A1 | APPLIANCES AND COMPOSITIONS FOR ORAL USE AND METHODS FOR TREATING THE ORAL MUCOSA, LIPS, AND PERIORAL REGIONS | JR Chem, LLC (US) | 2014-04-16 | — | — | EP | disclosed |
| WO-2012174076-A1 | APPLIANCES AND COMPOSITIONS FOR ORAL USE AND METHODS FOR TREATING THE ORAL MUCOSA, LIPS, AND PERIORAL REGIONS | JR CHEM, LLC (US) | 2012-12-20 | — | — | WO | disclosed |