Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10588951 | 0.73 | MAPT (0.42) | NPSR1L3MBTL1MAPTALDH1A1HTT | |
| SCHEMBL2859010 | 0.69 | ALDH1A1 (0.39) | NPSR1L3MBTL1MAPTALDH1A1HTT | |
| SCHEMBL3997502 | 0.69 | ALDH1A1 (0.39) | NPSR1L3MBTL1MAPTALDH1A1HTT | |
| SCHEMBL7915561 | 0.69 | NPSR1 (0.39) | NPSR1L3MBTL1MAPTALDH1A1HTT | |
| SCHEMBL123127 | 0.67 | ALDH1A1 (0.47) | MAPTALDH1A1HTTMAOAKDM4E | |
| SCHEMBL9336430 | 0.67 | ALDH1A1 (0.47) | MAPTALDH1A1HTTMAOAKDM4E | |
| SCHEMBL2324941 | 0.65 | — | — | |
| SCHEMBL2691041 | 0.65 | — | — | |
| SCHEMBL6668973 | 0.65 | ALDH1A1 (0.37) | NPSR1L3MBTL1MAPTALDH1A1HTT | |
| Water SCHEMBL4753900 | 0.65 | ALDH1A1 (0.45) | MAPTALDH1A1HTTMAOAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478623-B1 | NOVEL COUPLING AGENTS, THE ACTIVE INTERMEDIATES AND THE CONJUGATES THEREOF AND THE USE OF SAID CONJUGATES IN DIAGNOSTIC METHODS | BIOMERIEUX SA (FR) | 2011-03-23 | — | — | EP | disclosed |
| EP-1478623-A1 | NOVEL COUPLING AGENTS, THE ACTIVE INTERMEDIATES AND THE CONJUGATES THEREOF AND THE USE OF SAID CONJUGATES IN DIAGNOSTIC METHODS | BIOMERIEUX (FR) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003072546-A1 | NOVEL COUPLING AGENTS, THE ACTIVE INTERMEDIATES AND THE CONJUGATES THEREOF AND THE USE OF SAID CONJUGATES IN DIAGNOSTIC METHODS | bioMérieux (FR) | 2003-09-04 | — | — | WO | disclosed |