SCHEMBL2859010

SCHEMBL2859010

CC1(C)CC(=O)C(Cl)(Cl)C(=O)C1

nearest known ligand 0.40

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.39
MAPT P10636 3/20 0.39
KDM4E B2RXH2 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
HTT P42858 1/20 0.37
MAOA P21397 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
PKM P14618 1/20 0.33
POLB P06746 1/20 0.33
ATAD2 Q6PL18 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6668973 0.83 ALDH1A1 (0.37) ALDH1A1MAPTKDM4ENPSR1L3MBTL1
SCHEMBL3997502 0.77 ALDH1A1 (0.39) ALDH1A1MAPTKDM4ENPSR1L3MBTL1
SCHEMBL10588951 0.75 MAPT (0.42) ALDH1A1MAPTKDM4ENPSR1L3MBTL1
SCHEMBL7915561 0.71 NPSR1 (0.39) ALDH1A1MAPTKDM4ENPSR1L3MBTL1
SCHEMBL1424841 0.69 NPSR1 (0.38) ALDH1A1MAPTKDM4ENPSR1L3MBTL1
SCHEMBL2691041 0.67
SCHEMBL2324941 0.67
SCHEMBL20034217 0.67
SCHEMBL10527140 0.67
SCHEMBL4428965 0.66

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2173785-A1 HIGHLY CONDUCTIVE AND STABLE TRANSPARENT CONDUCTING POLYMER FILMS Imperial Innovations Limited (GB) 2010-04-14 EP claimed
WO-2009007361-A1 HIGHLY CONDUCTIVE AND STABLE TRANSPARENT CONDUCTING POLYMER FILMS IMPERIAL INNOVATIONS LIMITED (GB) 2009-01-15 WO claimed
WO-2024264021-A9 INHIBITION OF METHANE PRODUCTION IN RUMINANTS LOAM BIO LLC (US) 2025-02-27 WO disclosed
WO-2024264021-A2 INHIBITION OF METHANE PRODUCTION IN RUMINANTS LOAM BIO LLC (US) 2024-12-26 WO disclosed
CN-115612699-B Copolymer membrane, and enzymatic self-assembly synthesis method and application thereof in gas-liquid interface 中国科学院天津工业生物技术研究所 2024-10-25 CN disclosed
CN-115612114-B Copolymer membrane and method for enzymatic self-assembly synthesis and application thereof 中国科学院天津工业生物技术研究所 2024-02-20 CN disclosed
CN-115612403-B Self-assembled strong-adhesion copolymer film, coating method and application 中国科学院天津工业生物技术研究所 2023-12-01 CN disclosed
EP-4209485-A1 COMPOUND HAVING ANTITUMOR ACTIVITY AND USE THEREOF Innovstone Therapeutics Limited (CN) 2023-07-12 EP disclosed
CN-110760497-B Co-crosslinking immobilization method of chloroperoxidase 宁波大学 2023-03-21 CN disclosed
CN-115612114-A Copolymer membrane and enzymatic self-assembly synthesis method and application thereof 中国科学院天津工业生物技术研究所 2023-01-17 CN disclosed
CN-115612403-A Self-assembly strong-adhesion copolymer film, film coating method and application 中国科学院天津工业生物技术研究所 2023-01-17 CN disclosed
US-6355647-B1 INHIBIT THE SEROTONIN REUPTAKE. HYPERPROLACTINEMIA, VASOSPASMS, HYPERTENSION, GASTROINTESTINAL DISORDERS ASSOCIATED WITH MOTILITY AND SECRETION ABBOTT LABORATORIES 2002-03-12 US disclosed
US-20010019823-A1 ENZYME DETECTION/ASSAY METHOD AND SUBSTRATES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2001-09-06 US disclosed
WO-1997031008-A1 ENZYME DETECTION/ASSAY METHOD AND SUBSTRATES INDUSTRIAL RESEARCH LIMITED (NZ) 1997-08-28 WO disclosed
US-5521175-A CHOLECYSTOKININS AND GASTRIN ANTAGONIST FOR PHYSIOLOGICAL DISORDERS MERCK SHARP & DOHME LTD. (GB) 1996-05-28 US disclosed
WO-1991000724-A1 ALKYNYL AMINES THAT REGULATE CHOLINERGIC NEUROTRANSMISSION ABBOTT LABORATORIES (US) 1991-01-24 WO disclosed
US-4937191-A CULTURE PRODUCT OF DRESCHLERA AND CURVULARIA, UNINHIBITED OF HYDROGEN PEROXIDE AND HYPOHALOUS ACID CETUS CORPORATION (US) 1990-06-26 US disclosed
US-4937192-A ISOLATION FROM FERMENTATION CULTURE; EFFICIENCY CETUS CORPORATION (US) 1990-06-26 US disclosed
US-4707446-A OXIDATION CETUS CORPORATION (US) 1987-11-17 US disclosed
US-4707447-A OXIDATION, HALOGENATION CETUS CORPORATION (US) 1987-11-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010019823-A1 ENZYME DETECTION/ASSAY METHOD AND SUBSTRATES PNP, TREH, XDH ALDH1A1 2151/4885MAPT 4253/4885KDM4E 2051/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.