Methionine

Methionine

SCHEMBL14248751

CSCC[C@H](N)C(=O)O.Cc1cccc(O)c1.Oc1ccccc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 11/20 0.52
ACHE P22303 1/20 0.45
KYNU Q16719 1/20 0.44
SLC1A5 Q15758 1/20 0.43
GRIA2 P42262 1/20 0.43
CYP1A2 P05177 1/20 0.40
CYP2C19 P33261 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Racemethionine SCHEMBL14248750 1.00 KIF11 (0.52) KIF11ACHEKYNUSLC1A5GRIA2
Racemethionine SCHEMBL19283985 0.97 KIF11 (0.51) KIF11ACHEKYNUSLC1A5GRIA2
Methionine SCHEMBL19283981 0.97 KIF11 (0.51) KIF11ACHEKYNUSLC1A5GRIA2
Methionine SCHEMBL14976721 0.91 KIF11 (0.47) KIF11ACHEKYNUSLC1A5GRIA2
Racemethionine SCHEMBL14248767 0.89 KIF11 (0.51) KIF11KYNU
Methionine SCHEMBL14248774 0.89 KIF11 (0.51) KIF11KYNU
Methionine SCHEMBL28117610 0.86 KIF11 (0.54) KIF11
Racemethionine SCHEMBL28117612 0.86 KIF11 (0.54) KIF11
Methionine SCHEMBL15993778 0.78 KIF11 (0.43) KIF11SLC1A5
Racemethionine SCHEMBL27686953 0.78 BHMT (0.53) GRIA2CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2720712-A2 STABLE FORMULATIONS OF A HYALURONAN-DEGRADING ENZYME Halozyme, Inc. (US) 2014-04-23 EP disclosed
WO-2012174478-A9 STABLE FORMULATIONS OF A HYALURONAN-DEGRADING ENZYME HALOZYME, INC. (US) 2013-05-30 WO disclosed
WO-2012174478-A2 STABLE FORMULATIONS OF A HYALURONAN-DEGRADING ENZYME HALOZYME, INC. (US) 2012-12-20 WO disclosed