SCHEMBL1424909

SCHEMBL1424909

CCCCCCCCCCCCCCCCCCCc1cccc(CCCCCCCCCCCCCCCCCCC)c1O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.68
PTGS2 P35354 1/20 0.68
TYR P14679 2/20 0.61
LIPG Q9Y5X9 1/20 0.60
BID P55957 3/20 0.59
MCL1 Q07820 3/20 0.59
BCL2L1 Q07817 2/20 0.59
BAK1 Q16611 2/20 0.59
KAT8 Q9H7Z6 2/20 0.59
SAE1 Q9UBE0 2/20 0.59
PPARG P37231 1/20 0.59
PPARA Q07869 1/20 0.59
EP300 Q09472 1/20 0.59
KAT2A Q92830 1/20 0.59
KAT2B Q92831 1/20 0.59
KAT5 Q92993 1/20 0.59
GABRA1 P14867 1/20 0.54
GABRB2 P47870 1/20 0.54
TP53 P04637 2/20 0.53
CYP3A4 P08684 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11616767 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID
SCHEMBL11784149 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID
SCHEMBL4960231 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID
SCHEMBL11615237 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID
SCHEMBL199708 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID
SCHEMBL4962037 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID
SCHEMBL10926251 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID
SCHEMBL11618297 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID
SCHEMBL4959229 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID
SCHEMBL11621072 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3762452-A1 NEW POLYISOCYANATE COMPOSITIONS Vencorex France (FR) 2021-01-13 EP disclosed
WO-2019170674-A1 NEW POLYISOCYANATE COMPOSITIONS VENCOREX FRANCE (FR) 2019-09-12 WO disclosed
US-9932238-B2 Graphene and graphene oxide nano-environments for chemical reactions and atomic reformations PEERLESS WORLDWIDE, LLC (US) 2018-04-03 US disclosed
US-20150307971-A1 GRAPHENE AND GRAPHENE OXIDE NANO-ENVIRONMENTS FOR CHEMICAL REACTIONS AND ATOMIC REFORMATIONS PEERLESS WORLDWIDE, LLC (US) 2015-10-29 US disclosed
US-9023308-B2 Facile synthesis of graphene, graphene derivatives and abrasive nanoparticles and their various uses, including as tribologically-beneficial lubricant additives PEERLESS WORLDWIDE, LLC (US) 2015-05-05 US disclosed
US-8865113-B2 Facile synthesis of graphene, graphene derivatives and abrasive nanoparticles and their various uses, including as tribologically-beneficial lubricant additives PEERLESS WORLDWIDE, LLC (US) 2014-10-21 US disclosed
US-20140227211-A1 FACILE SYNTHESIS OF GRAPHENE, GRAPHENE DERIVATIVES AND ABRASIVE NANOPARTICLES AND THEIR VARIOUS USES, INCLUDING AS TRIBOLOGICALLY-BENEFICIAL LUBRICANT ADDITIVES PEERLESS WORLDWIDE, LLC (US) 2014-08-14 US disclosed
US-20140134092-A1 FACILE SYNTHESIS OF GRAPHENE, GRAPHENE DERIVATIVES AND ABRASIVE NANOPARTICLES AND THEIR VARIOUS USES, INCLUDING AS TRIBOLOGICALLY-BENEFICIAL LUBRICANT ADDITIVES SHANKMAN RICHARD S (US) 2014-05-15 US disclosed
EP-2118188-B1 POLYMER COMPOSITE EASTMAN KODAK CO (US) 2014-04-23 EP disclosed
EP-2686271-A1 FACILE SYNTHESIS OF GRAPHENE, GRAPHENE DERIVATIVES AND ABRASIVE NANOPARTICLES AND THEIR VARIOUS USES, INCLUDING AS TRIBOLOGICALLY-BENEFICIAL LUBRICANT ADDITIVES Peerless Worldwide, LLC (US) 2014-01-22 EP disclosed
WO-2012125854-A1 FACILE SYNTHESIS OF GRAPHENE, GRAPHENE DERIVATIVES AND ABRASIVE NANOPARTICLES AND THEIR VARIOUS USES, INCLUDING AS TRIBOLOGICALLY-BENEFICIAL LUBRICANT ADDITIVES PEERLESS WORLDWIDE, LLC (US) 2012-09-20 WO disclosed
EP-1844049-B1 LONG WAVELENGTH SHIFTED BENZOTRIAZOLE UV-ABSORBERS AND THEIR USE BASF SE (DE) 2011-03-23 EP disclosed
EP-2118188-A1 POLYMER COMPOSITE EASTMAN KODAK COMPANY (US) 2009-11-18 EP disclosed
US-7579396-B2 Polymer composite EASTMAN KODAK COMPANY (US) 2009-08-25 US disclosed
WO-2008094500-A1 POLYMER COMPOSITE EASTMAN KODAK COMPANY (US) 2008-08-07 WO disclosed
US-20080181969-A1 POLYMER COMPOSITE EASTMAN KODAK COMPANY 2008-07-31 US disclosed
US-7037964-B2 Polyolefin film compositions with permanent antifog properties CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-05-02 US disclosed
US-20040234801-A1 Polyolefin film compositions with permanent antifog properties TECHMER PM, LLC 2004-11-25 US disclosed
US-20030013784-A1 Stabilizer mixture GUGUMUS FRANCOIS (CH) 2003-01-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140227211-A1 FACILE SYNTHESIS OF GRAPHENE, GRAPHENE DERIVATIVES AND ABRASIVE NANOPARTICLES AND THEIR VARIOUS USES, INCLUDING AS TRIBOLOGICALLY-BENEFICIAL LUBRICANT ADDITIVES GRN, CCNO, TELO2 ALOX5 476/4885PTGS2 1274/4885TYR 1050/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.