SCHEMBL4960231

SCHEMBL4960231

CCCCCCCCCCc1cccc(CCCCCCCCCC)c1O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 2/20 0.68
▸ PTGS2 P35354 1/20 0.68
▸ TYR P14679 2/20 0.61
▸ LIPG Q9Y5X9 1/20 0.60
▸ BID P55957 3/20 0.59
▸ MCL1 Q07820 3/20 0.59
▸ BCL2L1 Q07817 2/20 0.59
▸ BAK1 Q16611 2/20 0.59
▸ KAT8 Q9H7Z6 2/20 0.59
▸ SAE1 Q9UBE0 2/20 0.59
▸ PPARG P37231 1/20 0.59
▸ PPARA Q07869 1/20 0.59
▸ EP300 Q09472 1/20 0.59
▸ KAT2A Q92830 1/20 0.59
▸ KAT2B Q92831 1/20 0.59
▸ KAT5 Q92993 1/20 0.59
▸ GABRA1 P14867 1/20 0.54
▸ GABRB2 P47870 1/20 0.54
▸ TP53 P04637 2/20 0.53
▸ CYP3A4 P08684 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11616767 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID
SCHEMBL4962037 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID
SCHEMBL4959229 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID
SCHEMBL11784149 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID
SCHEMBL11615237 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID
SCHEMBL10926251 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID
SCHEMBL199708 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID
SCHEMBL11621072 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID
SCHEMBL11618297 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID
SCHEMBL201162 1.00 ALOX5 (0.68) ALOX5PTGS2TYRLIPGBID

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015013456-A1 INDICATOR COMPOUNDS, POLYMERIZABLE DERIVATIVES THEREOF AND INFECTION INDICATING MEDICAL DEVICES COMPRISING THE SAME INDICATOR SYSTEMS INTERNATIONAL, INC. (US) 2015-01-29 — — WO disclosed
EP-1871844-B1 BUBBLE COMPOSITION WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2014-08-27 — — EP disclosed
EP-1871844-A2 NOVELTY COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C Technologies LLC (US) 2008-01-02 — — EP disclosed
US-7288585-B2 A polyolefin; natural or synthetic phyllosilicate or a mixture in nanoparticles, polymeric dispersing agent based on a long chain alkyl meth(acrylate), preferably a statistical, block or comb copolymer having hydrophilic and hydrophobic segments CIBA SPECIALTY CHEMICALS CORP. (US) 2007-10-30 — — US disclosed
US-7262319-B2 Phenolic antioxidants in crystalline form CIBA SPECIALTY CHEMICALS CORP. (US) 2007-08-28 — — US disclosed
WO-2007059350-A2 PREPARATION OF ALKOXYAMINES CARNEGIE MELLON UNIVERSITY (US) 2007-05-24 — — WO disclosed
WO-2007008389-A2 USE OF COLOR CHANGING INDICATORS IN CONSUMER PRODUCTS C2C TECHNOLOGIES LLC (US) 2007-01-18 — — WO disclosed
US-20070010400-A1 Use of color changing indicators in consumer products C2C TECHNOLOGIES, LLC 2007-01-11 — — US disclosed
US-20060257439-A1 Cleansing compositions with color changing indicator CRAYOLA LLC 2006-11-16 — — US disclosed
US-20060236470-A1 Novelty compositions with color changing indicator CRAYOLA LLC 2006-10-26 — — US disclosed
US-20060235127-A1 A polyolefin; natural or synthetic phyllosilicate or a mixture in nanoparticles, polymeric dispersing agent based on a long chain alkyl meth(acrylate), preferably a statistical, block or comb copolymer having hydrophilic and hydrophobic segments POLYMERS CRC LTD (AU) 2006-10-19 — — US disclosed
WO-2006105193-A2 PERSONAL CARE COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 — — WO disclosed
WO-2006105260-A1 ORAL CARE COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 — — WO disclosed
WO-2006105261-A1 CLEANSING COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 — — WO disclosed
WO-2006105191-A2 NOVELTY COMPOSITIONS WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2006-10-05 — — WO disclosed
US-20060222601-A1 Oral care compositions with color changing indicator C2C TECHNOLOGIES, LLC 2006-10-05 — — US disclosed
US-20060222675-A1 Personal care compositions with color changing indicator C2C TECHNOLOGIES, LLC 2006-10-05 — — US disclosed
US-20060189820-A1 Phenolic antioxidants in crystalline form CIBA SPECIALTY CHEMICALS CORPORATION 2006-08-24 — — US disclosed
US-4082808-A ANTIOXIDANTS, INTERMEDIATES FOR POLYESTERS, POLYCARBONATES, EPOXY RESINS GENERAL ELECTRIC COMPANY (US) 1978-04-04 — — US disclosed
US-3953519-A BASES, EPOXY COMPOUNDS, OLEFINS GENERAL ELECTRIC COMPANY (US) 1976-04-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060222675-A1 Personal care compositions with color changing indicator CUTA, POLR1C, TYR ALOX5 1179/4885PTGS2 3760/4885TYR 3/4885
US-20060257439-A1 Cleansing compositions with color changing indicator WASHC5, WASHC4, FHIT ALOX5 2388/4885PTGS2 3834/4885TYR 62/4885
US-20060189820-A1 Phenolic antioxidants in crystalline form HAAO, PPOX, PNPO ALOX5 78/4885PTGS2 1904/4885TYR 119/4885
US-20060222601-A1 Oral care compositions with color changing indicator CA9, CA7, TAS2R7 ALOX5 1235/4885PTGS2 2320/4885TYR 1525/4885
US-20070010400-A1 Use of color changing indicators in consumer products NQO2, CA4, CA7 ALOX5 1488/4885PTGS2 2913/4885TYR 50/4885
US-20060236470-A1 Novelty compositions with color changing indicator MITF, CRABP2, SHH ALOX5 1248/4885PTGS2 3241/4885TYR 9/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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