Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17936438 | 0.89 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1TSHRMAPTMAPK1 | |
| SCHEMBL762575 | 0.87 | MAPT (0.52) | SMN1; SMN2ALDH1A1TSHRMAPTMAPK1 | |
| SCHEMBL2087478 | 0.86 | KDM4E (0.54) | SMN1; SMN2ALDH1A1TSHRMAPTMAPK1 | |
| SCHEMBL7015793 | 0.85 | MAPT (0.48) | SMN1; SMN2ALDH1A1TSHRMAPTMAPK1 | |
| SCHEMBL2332528 | 0.85 | TSHR (0.58) | SMN1; SMN2ALDH1A1TSHRMAPTMAPK1 | |
| SCHEMBL23273490 | 0.85 | MEN1 (0.52) | SMN1; SMN2ALDH1A1TSHRMAPTMAPK1 | |
| SCHEMBL27325815 | 0.84 | MAPT (0.47) | SMN1; SMN2ALDH1A1MAPTMAPK1L3MBTL1 | |
| SCHEMBL1058323 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1TSHRMAPTMAPK1 | |
| SCHEMBL3668560 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1TSHRMAPTMAPK1 | |
| SCHEMBL2085072 | 0.84 | TSHR (0.51) | SMN1; SMN2ALDH1A1TSHRMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012172043-A1 | PURINE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS FOR PREVENTION OR TREATMENT OF BACTERIAL INFECTIONS | LABORATOIRE BIODIM (FR) | 2012-12-20 | — | — | WO | disclosed |