Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15242469 | 0.82 | CA1 (0.42) | KDM4ETSHRHDAC4HDAC8ALDH1A1 | |
| SCHEMBL10397110 | 0.81 | KDM4E (0.36) | KDM4ETSHRALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL3901324 | 0.80 | LMNA (0.38) | TSHRALDH1A1SMN1; SMN2LMNACA1 | |
| SCHEMBL30345552 | 0.79 | PTGS1 (0.56) | KDM4ETSHRHDAC4HDAC8ALDH1A1 | |
| SCHEMBL11063307 | 0.79 | PTGS1 (0.56) | KDM4ETSHRHDAC4HDAC8ALDH1A1 | |
| SCHEMBL9776758 | 0.78 | AOC3 (0.34) | KDM4ETSHRPTGS1CASR | |
| SCHEMBL15849013 | 0.77 | PTGS1 (0.55) | KDM4ETSHRHDAC4HDAC8ALDH1A1 | |
| SCHEMBL30601580 | 0.77 | HDAC4 (0.55) | KDM4ETSHRHDAC4HDAC8ALDH1A1 | |
| SCHEMBL84440 | 0.77 | HDAC4 (0.55) | KDM4ETSHRHDAC4HDAC8ALDH1A1 | |
| SCHEMBL21230476 | 0.75 | KDM4E (0.49) | KDM4ETSHRHDAC4HDAC8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7343073-B2 | Optical members and compositions for producing them | FUJIFILM CORPORATION (JP) | 2008-03-11 | — | — | US | disclosed |