⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13900379 | 0.85 | — | — | |
| SCHEMBL13900394 | 0.81 | LMNA (0.33) | — | |
| SCHEMBL20254156 | 0.81 | LMNA (0.33) | — | |
| SCHEMBL20254201 | 0.79 | — | — | |
| SCHEMBL20254204 | 0.79 | — | — | |
| SCHEMBL19197217 | 0.79 | — | — | |
| SCHEMBL20254154 | 0.79 | — | — | |
| SCHEMBL20254250 | 0.79 | — | — | |
| SCHEMBL19197216 | 0.79 | — | — | |
| SCHEMBL20254152 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7348436-B2 | Compounds useful for the synthesis of (+)-discodermolide and methods thereof | KOSAN BIOSCIENCES INCORPORATED (US) | 2008-03-25 | — | — | US | disclosed |
| US-7348436-B2 | Compounds useful for the synthesis of (+)-discodermolide and methods thereof | KOSAN BIOSCIENCES INCORPORATED (US) | 2008-03-25 | — | — | US | disclosed |