SCHEMBL20254156

SCHEMBL20254156

C[C@@H]1C(=O)O[C@H](CO)[C@H](C)C1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.33
▸ GBA1 P04062 1/20 0.33
▸ PRKCA P17252 2/20 0.32
▸ PRKD3 O94806 1/20 0.32
▸ PRKCG P05129 1/20 0.32
▸ PRKCB P05771 1/20 0.32
▸ PRKCH P24723 1/20 0.32
▸ PRKCE Q02156 1/20 0.32
▸ PRKCQ Q04759 1/20 0.32
▸ PRKCD Q05655 1/20 0.32
▸ PRKD1 Q15139 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13900394 1.00 LMNA (0.33) LMNAGBA1PRKCAPRKD3PRKCG
SCHEMBL20254152 0.89 — —
SCHEMBL20254201 0.89 — —
SCHEMBL19197648 0.89 — —
SCHEMBL20254154 0.89 — —
SCHEMBL20254190 0.89 — —
SCHEMBL20254173 0.89 — —
SCHEMBL20254250 0.89 — —
SCHEMBL19197217 0.89 — —
SCHEMBL20254204 0.89 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230183274-A1 SCALABLE POLYPROPIONATE LACTONE STEREOTETRADS AKANOCURE PHARMACEUTICALS, INC. (US) 2023-06-15 — — US disclosed
US-20210277032-A1 SCALABLE POLYPROPIONATE LACTONE STEREOTETRADS AKANOCURE PHARMACEUTICALS, INC. (US) 2021-09-09 — — US disclosed
US-10851121-B2 Scalable polypropionate lactone stereotetrads AKANOCURE PHAMRACEUTICALS, INC. (US) 2020-12-01 — — US disclosed
WO-2018107180-A1 SCALABLE POLYPROPIONATE LACTONE STEREOTETRADS AKANOCURE PHARMACEUTICALS, INC. (US) 2018-06-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230183274-A1 SCALABLE POLYPROPIONATE LACTONE STEREOTETRADS SBDS, STS, ADCYAP1R1 LMNA 4539/4885GBA1 2119/4885PRKCA 4435/4885
US-20210277032-A1 SCALABLE POLYPROPIONATE LACTONE STEREOTETRADS SBDS, STS, ADCYAP1R1 LMNA 4539/4885GBA1 2119/4885PRKCA 4435/4885
US-10851121-B2 Scalable polypropionate lactone stereotetrads SBDS, STS, ADCYAP1R1 LMNA 4539/4885GBA1 2119/4885PRKCA 4435/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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