Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | PDE2A | O00408 | 4/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | NT5E | P21589 | 5/20 | 0.44 |
| ▸ | CD99 | P14209 | 1/20 | 0.44 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.42 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.42 |
| ▸ | IARS1 | P41252 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4758281 | 0.91 | ADORA3 (0.56) | ADORA3CA1CA2CA4CA9 | |
| SCHEMBL4758255 | 0.81 | ADORA3 (0.56) | ADORA3CA1CA2CA4CA9 | |
| SCHEMBL4758245 | 0.79 | ADORA3 (0.54) | ADORA3CA1CA2CA4CA9 | |
| SCHEMBL4759360 | 0.77 | ADORA3 (0.57) | ADORA3CA1CA2CA4CA9 | |
| SCHEMBL4757814 | 0.76 | ADORA3 (0.56) | ADORA3CA1CA2CA4CA9 | |
| SCHEMBL24026358 | 0.74 | ADORA3 (0.59) | ADORA3CA1CA2CA4CA9 | |
| SCHEMBL14252588 | 0.73 | ADORA3 (0.74) | ADORA3CA1CA2CA4CA9 | |
| SCHEMBL7198801 | 0.69 | ADORA3 (0.72) | ADORA3CA1CA2CA4CA9 | |
| SCHEMBL3437027 | 0.69 | ADORA3 (0.72) | ADORA3CA1CA2CA4CA9 | |
| SCHEMBL19470039 | 0.69 | DNMT1 (0.48) | ADORA2AADORA2BALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7342003-B2 | Synthesis of 2-aralkyloxyadenosines, 2-alkoxyadenosines, and their analogs | KING PHARMACEUTICALS RESEARCH AND DEVELOPMENT, INC. (US) | 2008-03-11 | — | — | US | disclosed |